Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   WDR05_RS16950 Genome accession   NZ_CP149444
Coordinates   3246991..3248367 (-) Length   458 a.a.
NCBI ID   WP_029725912.1    Uniprot ID   -
Organism   Bacillus subtilis strain HC-9     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3241991..3253367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WDR05_RS16925 (WDR05_16905) feuV 3242032..3242859 (-) 828 WP_010886609.1 ABC transporter ATP-binding protein -
  WDR05_RS16930 (WDR05_16910) cotNW 3243077..3243514 (-) 438 WP_029725909.1 YusW family protein -
  WDR05_RS16935 (WDR05_16915) - 3243624..3245420 (-) 1797 WP_029725910.1 M3 family oligoendopeptidase -
  WDR05_RS16940 (WDR05_16920) yusZ 3245555..3246397 (+) 843 WP_029725911.1 oxidoreductase -
  WDR05_RS16945 (WDR05_16925) mrgA 3246487..3246948 (+) 462 WP_015714679.1 metalloregulation DNA-binding stress protein MgrA -
  WDR05_RS16950 (WDR05_16930) htrA 3246991..3248367 (-) 1377 WP_029725912.1 serine protease Do-like protein HtrB Regulator
  WDR05_RS16955 (WDR05_16935) cssR 3248645..3249322 (+) 678 WP_003228529.1 secretion stress-responsive two-component system response regulator CssR -
  WDR05_RS16960 (WDR05_16940) cssS 3249319..3250674 (+) 1356 WP_003228527.1 secretion stress-responsive two-component system sensor histidine kinase CssS -
  WDR05_RS16965 (WDR05_16945) spxO 3250702..3250866 (-) 165 WP_003221681.1 anti-adapter protein SpxO -
  WDR05_RS16970 (WDR05_16950) spxN 3251034..3251909 (+) 876 WP_003243192.1 TetR/AcrR family transcriptional regulator -
  WDR05_RS16975 (WDR05_16955) fumC 3251949..3253337 (-) 1389 WP_003228523.1 class II fumarate hydratase -

Sequence

Protein


Download         Length: 458 a.a.        Molecular weight: 48747.21 Da        Isoelectric Point: 4.5582

>NTDB_id=873934 WDR05_RS16950 WP_029725912.1 3246991..3248367(-) (htrA) [Bacillus subtilis strain HC-9]
MDYRRDGQNDQHQTEPSHTEQQNTENQKLIGHSEQELLDAPVSYEAGRQETASALEMEKQETAVKKEKKRRAAWLSPILG
GIIGGGLMLGIAPYLPSDQNQTTETASANKQVQSDNFTTAPITNASNIADMVEDLEPTIVGISNIQTSQNNTFGTGGGSS
SESESGTGSGVIFKKDSDKAYIITNNHVVEGANKLTVTLYNGETETAKLVGSDTITDLAVLEISGKNVKKVASFGDSSQL
RTGEKVIAIGNPLGQQFSGTVTQGIISGLNRTIDVDTTQGTVEMNVLQTDAAINPGNSGGPLINASGQVIGINSLKVSES
GVESLGFAIPSNDVEPIVDQLLQNGKVDRPFLGVQMIDMSQVPETYQENTLGLFGDQLGKGVYVKEVQANSPAEKAGIKS
EDVIVKLNGKDVESSADIRQILYKDLKVGDKTTIQVLRKGKTKTLNATLTKQTESSSS

Nucleotide


Download         Length: 1377 bp        

>NTDB_id=873934 WDR05_RS16950 WP_029725912.1 3246991..3248367(-) (htrA) [Bacillus subtilis strain HC-9]
TTGGATTATCGACGTGATGGCCAAAACGATCAACATCAAACTGAACCTTCACATACAGAACAGCAGAATACAGAAAACCA
GAAGCTGATTGGACATTCTGAACAAGAATTGCTTGACGCGCCTGTGTCGTATGAAGCGGGACGGCAGGAAACGGCTTCTG
CTTTAGAAATGGAAAAGCAAGAAACGGCTGTGAAAAAAGAAAAGAAACGGAGAGCCGCATGGCTGAGCCCGATTTTAGGC
GGTATTATCGGCGGGGGCCTCATGCTTGGCATCGCGCCTTATCTGCCGTCAGACCAAAATCAGACGACCGAGACCGCTTC
CGCAAATAAACAGGTGCAGTCTGATAATTTTACAACGGCGCCGATAACGAACGCATCAAACATCGCTGATATGGTAGAGG
ATTTAGAGCCTACGATTGTCGGAATCTCAAATATCCAAACCTCTCAAAATAACACATTCGGCACGGGAGGAGGCTCCAGC
TCAGAAAGTGAAAGCGGAACCGGTTCAGGTGTCATTTTCAAAAAAGACAGCGATAAAGCGTATATCATTACAAACAACCA
TGTCGTTGAAGGCGCGAACAAGCTGACTGTTACGCTATACAACGGAGAAACGGAAACTGCCAAGCTTGTCGGCAGCGATA
CCATTACTGATTTGGCAGTTTTGGAAATCAGCGGCAAGAACGTCAAAAAAGTGGCGAGCTTTGGTGATTCTTCGCAGCTG
CGCACTGGCGAAAAGGTAATCGCTATCGGTAACCCGCTCGGACAGCAGTTTTCCGGTACGGTGACACAAGGCATCATTAG
CGGACTGAACCGGACAATTGATGTGGATACAACACAAGGGACGGTGGAAATGAACGTGCTGCAAACCGATGCAGCGATCA
ATCCGGGGAACAGCGGAGGCCCATTAATCAATGCAAGCGGCCAGGTCATCGGCATCAACAGCTTGAAGGTGAGCGAAAGC
GGCGTGGAATCACTTGGATTTGCGATCCCAAGCAATGATGTCGAGCCAATTGTTGACCAGCTGCTGCAAAACGGGAAGGT
GGACCGTCCGTTTTTAGGCGTGCAGATGATTGACATGTCACAAGTTCCTGAAACCTATCAGGAAAATACGCTCGGCCTGT
TTGGAGATCAATTGGGCAAAGGTGTTTATGTAAAAGAAGTTCAAGCAAATTCGCCGGCAGAAAAAGCAGGTATTAAATCT
GAGGATGTCATTGTCAAACTAAACGGTAAAGACGTGGAAAGCAGTGCGGATATCCGTCAGATCCTTTACAAAGACTTAAA
AGTCGGAGATAAAACAACAATCCAAGTGCTGCGAAAGGGAAAAACGAAAACGTTGAACGCGACACTGACCAAGCAGACAG
AAAGCAGTTCAAGCTAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(350-449)

Trypsin-like peptidase domain (Trypsin_2)

(168-312)

Peptidase family M50 (Peptidase_M50)

(282-455)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

41.353

87.118

0.36