Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WDR05_RS03010 Genome accession   NZ_CP149444
Coordinates   575573..576214 (+) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis strain HC-9     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 570573..581214
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WDR05_RS02980 (WDR05_02990) ydfE 571766..572389 (-) 624 WP_029317354.1 flavin reductase family protein -
  WDR05_RS02985 (WDR05_02995) ydfF 572479..573159 (+) 681 WP_003244115.1 helix-turn-helix transcriptional regulator -
  WDR05_RS02990 (WDR05_03000) ydfG 573239..573682 (-) 444 WP_014478970.1 carboxymuconolactone decarboxylase family protein -
  WDR05_RS02995 (WDR05_03005) - 573770..573946 (-) 177 WP_080348091.1 hypothetical protein -
  WDR05_RS03000 (WDR05_03010) - 573943..574086 (-) 144 WP_014478971.1 hypothetical protein -
  WDR05_RS03005 (WDR05_03015) ydfH 574357..575580 (+) 1224 WP_015252722.1 two-component system sensor histidine kinase YdfH -
  WDR05_RS03010 (WDR05_03020) vraR 575573..576214 (+) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  WDR05_RS03015 (WDR05_03025) pleJ 576330..578504 (+) 2175 WP_032678643.1 MMPL family transporter -
  WDR05_RS03020 (WDR05_03030) cesA 578917..579818 (-) 902 Protein_547 carboxylesterase -
  WDR05_RS03025 (WDR05_03035) ydfK 580021..580710 (-) 690 WP_033883509.1 DUF554 domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=873834 WDR05_RS03010 WP_003244318.1 575573..576214(+) (vraR) [Bacillus subtilis strain HC-9]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=873834 WDR05_RS03010 WP_003244318.1 575573..576214(+) (vraR) [Bacillus subtilis strain HC-9]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTCGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAAGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCGATCAGAGGAAATGTGCTATTGCAGCCTGATATCCTCAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCAAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362