Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RAM40_RS05445 Genome accession   NZ_CP132400
Coordinates   1154711..1155427 (-) Length   238 a.a.
NCBI ID   WP_014613411.1    Uniprot ID   X2JA42
Organism   Staphylococcus pseudintermedius strain CUVET16-496     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1149711..1160427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RAM40_RS05430 (RAM40_05370) - 1151216..1152163 (+) 948 WP_014613408.1 LacI family DNA-binding transcriptional regulator -
  RAM40_RS05435 (RAM40_05375) - 1152219..1153703 (+) 1485 WP_014613409.1 sucrose-6-phosphate hydrolase -
  RAM40_RS05440 (RAM40_05380) - 1153707..1154651 (+) 945 WP_404968683.1 carbohydrate kinase -
  RAM40_RS05445 (RAM40_05385) agrA 1154711..1155427 (-) 717 WP_014613411.1 quorum-sensing response regulator AgrA Regulator
  RAM40_RS05450 (RAM40_05390) agrC 1155441..1156733 (-) 1293 WP_015729415.1 quorum-sensing sensor histidine kinase AgrC -
  RAM40_RS05455 (RAM40_05395) agrD 1156757..1156894 (-) 138 WP_014613413.1 cyclic lactone autoinducer peptide AgrD -
  RAM40_RS05460 (RAM40_05400) - 1156896..1157462 (-) 567 WP_014613414.1 accessory gene regulator AgrB -
  RAM40_RS05465 - 1157854..1157934 (+) 81 WP_110144734.1 delta-lysin family phenol-soluble modulin -
  RAM40_RS05470 (RAM40_05405) - 1158218..1159021 (-) 804 WP_014613416.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 28002.15 Da        Isoelectric Point: 5.4331

>NTDB_id=869118 RAM40_RS05445 WP_014613411.1 1154711..1155427(-) (agrA) [Staphylococcus pseudintermedius strain CUVET16-496]
MKILICEDDPKQRERMVSIIENYIMIEEKPMKIELATNDPYAILETSKNMTDIGCYFLDIQLESDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPEELRTRIIDCLETALKRLDLLTKDHTVETLELKRGTSSVYVNYDDVM
FFESSPKSHRLIAHLDNRQIEFYGNLKELAQLDDRFFRCHNSYVLNRRNITSVDTKERIAYFKNEEFCYVSVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=869118 RAM40_RS05445 WP_014613411.1 1154711..1155427(-) (agrA) [Staphylococcus pseudintermedius strain CUVET16-496]
ATGAAAATTTTGATTTGTGAGGATGATCCTAAACAACGCGAACGTATGGTGTCCATTATTGAAAACTATATTATGATTGA
AGAGAAGCCGATGAAAATTGAGCTTGCTACCAATGACCCTTATGCTATCTTAGAAACTTCTAAAAACATGACTGATATTG
GCTGCTACTTTTTAGATATTCAATTAGAGTCTGATATTAACGGGATTAAATTAGGGAGCGAAATTCGTAAGCACGATCCT
GTTGGGAATATTATTTTTGTGACGAGTCATAGTGAGCTGACGTACTTGACGTTTGTCTATAAAGTGGCTGCCATGGATTT
TATTTTTAAAGATGATCCTGAAGAATTAAGGACACGCATTATCGATTGTTTAGAAACAGCATTAAAACGGCTTGATTTAT
TAACAAAAGATCATACTGTTGAAACTTTGGAACTCAAACGTGGAACAAGCTCGGTTTACGTGAACTATGACGACGTGATG
TTTTTCGAGTCTTCACCGAAGTCACATCGTTTAATCGCGCATTTAGACAATCGTCAAATCGAATTTTACGGCAATTTGAA
AGAGTTAGCTCAACTCGATGATCGATTCTTCAGATGCCACAACAGTTATGTGCTAAACAGAAGAAATATTACAAGTGTCG
ATACGAAAGAACGGATTGCTTATTTCAAAAATGAAGAATTTTGTTACGTGTCGGTGCGTAATTTGAAGAAAATTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(152-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB X2JA42

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

83.193

100

0.832