Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RAM43_RS04430 Genome accession   NZ_CP132394
Coordinates   949328..950044 (-) Length   238 a.a.
NCBI ID   WP_014613411.1    Uniprot ID   X2JA42
Organism   Staphylococcus pseudintermedius strain CUVET18-689     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 944328..955044
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RAM43_RS04415 (RAM43_04370) - 945833..946780 (+) 948 WP_014613408.1 LacI family DNA-binding transcriptional regulator -
  RAM43_RS04420 (RAM43_04375) - 946836..948320 (+) 1485 WP_014613409.1 sucrose-6-phosphate hydrolase -
  RAM43_RS04425 (RAM43_04380) - 948324..949268 (+) 945 WP_014613410.1 carbohydrate kinase family protein -
  RAM43_RS04430 (RAM43_04385) agrA 949328..950044 (-) 717 WP_014613411.1 quorum-sensing response regulator AgrA Regulator
  RAM43_RS04435 (RAM43_04390) agrC 950058..951350 (-) 1293 WP_015729415.1 quorum-sensing sensor histidine kinase AgrC -
  RAM43_RS04440 (RAM43_04395) agrD 951374..951511 (-) 138 WP_014613413.1 cyclic lactone autoinducer peptide AgrD -
  RAM43_RS04445 (RAM43_04400) - 951513..952079 (-) 567 WP_014613414.1 accessory gene regulator AgrB -
  RAM43_RS04450 - 952471..952551 (+) 81 WP_110144734.1 delta-lysin family phenol-soluble modulin -
  RAM43_RS04455 (RAM43_04405) - 952835..953638 (-) 804 WP_014613416.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 28002.15 Da        Isoelectric Point: 5.4331

>NTDB_id=869049 RAM43_RS04430 WP_014613411.1 949328..950044(-) (agrA) [Staphylococcus pseudintermedius strain CUVET18-689]
MKILICEDDPKQRERMVSIIENYIMIEEKPMKIELATNDPYAILETSKNMTDIGCYFLDIQLESDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPEELRTRIIDCLETALKRLDLLTKDHTVETLELKRGTSSVYVNYDDVM
FFESSPKSHRLIAHLDNRQIEFYGNLKELAQLDDRFFRCHNSYVLNRRNITSVDTKERIAYFKNEEFCYVSVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=869049 RAM43_RS04430 WP_014613411.1 949328..950044(-) (agrA) [Staphylococcus pseudintermedius strain CUVET18-689]
ATGAAAATTTTGATTTGTGAGGATGATCCTAAACAACGCGAACGTATGGTGTCCATTATTGAAAACTATATTATGATTGA
AGAGAAGCCGATGAAAATTGAGCTTGCTACCAATGACCCTTATGCTATCTTAGAAACTTCTAAAAACATGACTGATATTG
GCTGCTACTTTTTAGATATTCAATTAGAGTCTGATATTAACGGGATTAAATTAGGGAGCGAAATTCGTAAGCACGATCCT
GTTGGGAATATTATTTTTGTGACGAGTCATAGTGAGCTGACGTACTTGACGTTTGTCTATAAAGTGGCTGCCATGGATTT
TATTTTTAAAGATGATCCTGAAGAATTAAGGACACGCATTATCGATTGTTTAGAAACAGCATTAAAACGGCTTGATTTAT
TAACAAAAGATCATACTGTTGAAACTTTGGAACTCAAACGTGGAACAAGCTCGGTTTACGTGAACTATGACGACGTGATG
TTTTTCGAGTCTTCACCGAAGTCACATCGTTTAATCGCGCATTTAGACAATCGTCAAATCGAATTTTACGGCAATTTGAA
AGAGTTAGCTCAACTCGATGATCGATTCTTCAGATGCCACAACAGTTATGTGCTAAACAGAAGAAATATTACAAGTGTCG
ATACGAAAGAACGGATTGCTTATTTCAAAAATGAAGAATTTTGTTACGTGTCGGTGCGTAATTTGAAGAAAATTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(152-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB X2JA42

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

83.193

100

0.832