Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RAM42_RS04655 Genome accession   NZ_CP132389
Coordinates   956971..957687 (-) Length   238 a.a.
NCBI ID   WP_096533945.1    Uniprot ID   X2JBZ6
Organism   Staphylococcus pseudintermedius strain CUVET16-793     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 951971..962687
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RAM42_RS04640 (RAM42_04600) - 953476..954423 (+) 948 WP_020220433.1 LacI family DNA-binding transcriptional regulator -
  RAM42_RS04645 (RAM42_04605) - 954479..955963 (+) 1485 WP_020220432.1 sucrose-6-phosphate hydrolase -
  RAM42_RS04650 (RAM42_04610) - 955967..956911 (+) 945 WP_020220431.1 carbohydrate kinase family protein -
  RAM42_RS04655 (RAM42_04615) agrA 956971..957687 (-) 717 WP_096533945.1 quorum-sensing response regulator AgrA Regulator
  RAM42_RS04660 agrC 957701..958993 (-) 1293 WP_096533946.1 quorum-sensing sensor histidine kinase AgrC -
  RAM42_RS04665 (RAM42_04625) agrD 959016..959153 (-) 138 WP_019166405.1 cyclic lactone autoinducer peptide AgrD -
  RAM42_RS04670 (RAM42_04630) - 959155..959721 (-) 567 WP_096533948.1 accessory gene regulator AgrB -
  RAM42_RS04675 - 960113..960190 (+) 78 WP_126511050.1 delta-lysin family phenol-soluble modulin -
  RAM42_RS04680 (RAM42_04635) - 960478..961281 (-) 804 WP_096533951.1 carbon-nitrogen family hydrolase -
  RAM42_RS04685 (RAM42_04640) - 961446..962315 (+) 870 WP_234985398.1 hypothetical protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 28017.12 Da        Isoelectric Point: 5.0936

>NTDB_id=868949 RAM42_RS04655 WP_096533945.1 956971..957687(-) (agrA) [Staphylococcus pseudintermedius strain CUVET16-793]
MKILICEDDPKQRERMVSIIENYIMIEEKPMEIELATNDPYAILETSKNMTDIGCYFLDIQLESDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPEELRTRIIDCLETALKRLDLLTKDHTVETLELKRGTSSVYVNYDDVM
FFESSPKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSYVLNRRNITSVDTKERIAYFKNEEFCYVSVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=868949 RAM42_RS04655 WP_096533945.1 956971..957687(-) (agrA) [Staphylococcus pseudintermedius strain CUVET16-793]
ATGAAAATTTTGATTTGTGAGGATGATCCTAAACAACGCGAACGCATGGTGTCCATTATTGAAAACTATATTATGATTGA
AGAGAAGCCGATGGAAATTGAGCTTGCTACCAATGACCCTTATGCTATTTTAGAAACTTCTAAAAACATGACTGATATTG
GCTGCTACTTTTTAGATATTCAATTAGAGTCTGATATTAACGGGATTAAATTAGGGAGCGAAATTCGTAAGCACGATCCT
GTTGGGAATATTATTTTTGTGACGAGTCATAGTGAGCTGACGTACTTGACGTTTGTCTATAAAGTGGCTGCCATGGATTT
TATTTTTAAAGATGATCCTGAAGAATTAAGAACACGCATTATCGATTGTTTAGAAACAGCATTAAAACGGCTTGATTTGT
TAACAAAAGATCATACTGTTGAAACTTTGGAACTCAAACGTGGAACAAGCTCAGTTTACGTGAACTATGACGACGTGATG
TTTTTCGAGTCCTCACCGAAGTCACATCGTTTAATCGCGCATTTAGACAATCGTCAAATCGAATTTTACGGCAATTTGAA
AGAGTTAGCTCAACTCGATGAGCGATTCTTCAGATGCCACAACAGTTATGTGCTAAACAGAAGAAATATTACAAGTGTCG
ATACGAAAGAACGGATTGCTTATTTCAAAAATGAAGAATTTTGTTACGTGTCGGTGCGTAATTTGAAGAAAATTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(152-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB X2JBZ6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

83.193

100

0.832