Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   WHP78_RS02855 Genome accession   NZ_CP148250
Coordinates   558705..560507 (+) Length   600 a.a.
NCBI ID   WP_002876788.1    Uniprot ID   -
Organism   Campylobacter jejuni strain Z1323CCJ0008     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 553705..565507
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHP78_RS02840 (WHP78_02840) - 554998..556458 (-) 1461 WP_002866246.1 hypothetical protein -
  WHP78_RS02845 (WHP78_02845) guaA 556544..558079 (-) 1536 WP_002866245.1 glutamine-hydrolyzing GMP synthase -
  WHP78_RS02850 (WHP78_02850) - 558218..558712 (+) 495 WP_002866244.1 hypothetical protein -
  WHP78_RS02855 (WHP78_02855) uvrC 558705..560507 (+) 1803 WP_002876788.1 excinuclease ABC subunit UvrC Machinery gene
  WHP78_RS02860 (WHP78_02860) - 560509..561705 (+) 1197 WP_002876789.1 hypothetical protein -
  WHP78_RS02865 (WHP78_02865) - 561702..562604 (-) 903 WP_002866239.1 radical SAM protein -
  WHP78_RS02870 (WHP78_02870) hemE 562601..563623 (-) 1023 WP_002876790.1 uroporphyrinogen decarboxylase -
  WHP78_RS02875 (WHP78_02875) ciaC 563803..564123 (-) 321 WP_002876791.1 invasion antigen CiaC -
  WHP78_RS02880 (WHP78_02880) - 564179..565378 (-) 1200 WP_249617095.1 MFS transporter -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69748.82 Da        Isoelectric Point: 9.3105

>NTDB_id=868941 WHP78_RS02855 WP_002876788.1 558705..560507(+) (uvrC) [Campylobacter jejuni strain Z1323CCJ0008]
MTKENLENELKTLPNSAGVYQYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPRNSLRIQKMIEETVHLEFITTNSE
ADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFEEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQK
ASCKSPCIFYQISRCLAPCDKRISREKYLEILDEAMHALLNPSILIKNLEKQMLVLAQNENYEEAAKVRDQIVTIKDLEV
KVEIDIAKLEDFEVFALAFENSMLSTLRFVVQNGKIISVNSKITPIKNDIQWDKNEIYKQLILENFSMDIPLLANVIYVY
EEFEDRMLLEEILSQRFDKKISIKIPKIGEKRRICDLAFQNALLNIEKEQKNHDFTIQKELKSYFELENLPNDIEIFDNS
HLQGMANVGAMVTYSANSWDKSKYRKFHLKHKNDYDQMREVLMRRALDFDKIPPPDLWLIDGGKALLDLAKEIIVSSGAN
VDILAISKEKIDAKAHRAKGGARDKIHSLKGEFSLSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLNSSKLVNLGLS
SGVIQKLLAYYGNFESIYKADFKDLAMLVGKKVAQKIKEN

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=868941 WHP78_RS02855 WP_002876788.1 558705..560507(+) (uvrC) [Campylobacter jejuni strain Z1323CCJ0008]
TTGACTAAAGAGAATTTAGAAAATGAGTTAAAAACTCTTCCTAATAGTGCTGGAGTGTATCAATATTTTAATCAAGAAGG
AAAGCTTTTATATGTAGGTAAGGCTAAAAATCTTAAAAATCGTGTCAAATCTTATTTCGCTTTTACTCCAAATTTACATG
CAAACCCAAGAAATTCTTTAAGAATTCAAAAAATGATTGAAGAAACAGTGCATTTGGAATTTATCACTACTAATTCAGAA
GCCGATGCTTTGATTTTGGAAAATTCTTTTATCAAACAACTGCATCCAAAATATAATATTTTACTAAGAGATGATAAAAC
TTATCCTTATATTTATGTGGATTTTGAAGAAGAATTTCCACGCTTTGAGATCACTAGAAAATTAGTAAAAAAAAGCAAAA
TTAAATATTTTGGCCCTTTTTTTAAAGGCGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCTTTAAAGCAAAAA
GCAAGTTGTAAATCCCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCGCCTTGTGATAAACGCATTAGCAGGGAAAA
ATACCTTGAAATTTTAGATGAGGCTATGCACGCGCTTTTAAATCCTAGTATTTTAATAAAAAATTTAGAAAAACAAATGC
TTGTTTTAGCACAGAATGAAAATTATGAAGAAGCAGCTAAAGTAAGAGATCAGATTGTAACGATTAAGGATTTAGAAGTT
AAGGTTGAAATAGATATTGCAAAATTAGAAGATTTTGAAGTATTTGCTTTAGCTTTTGAAAATTCCATGCTTTCAACCTT
GCGTTTTGTAGTGCAAAATGGAAAAATTATCAGTGTAAATTCTAAGATTACTCCTATAAAAAATGATATACAATGGGATA
AAAATGAAATTTATAAGCAACTGATTTTAGAAAATTTTAGCATGGATATTCCTTTGCTTGCAAATGTTATTTATGTTTAT
GAAGAATTTGAAGATAGAATGCTTTTAGAAGAAATTTTAAGCCAAAGGTTTGATAAAAAAATCAGTATTAAAATCCCTAA
AATAGGAGAAAAAAGAAGAATTTGTGATTTGGCTTTTCAAAATGCCCTTTTAAATATAGAAAAAGAGCAAAAAAATCATG
ATTTTACTATACAAAAAGAATTAAAGTCTTATTTTGAGCTTGAAAATTTACCAAATGATATAGAAATTTTTGATAATTCT
CATTTGCAAGGCATGGCAAATGTTGGAGCTATGGTAACTTATAGTGCAAATTCTTGGGATAAGTCAAAATATCGCAAATT
TCATTTAAAACATAAAAATGATTATGATCAAATGCGTGAAGTTTTAATGCGTAGGGCTTTGGACTTTGATAAAATACCCC
CTCCTGATTTATGGCTTATAGATGGAGGCAAGGCTTTGCTTGATTTGGCTAAAGAAATCATTGTAAGTAGTGGGGCAAAT
GTCGATATTTTAGCTATTTCAAAAGAAAAAATCGATGCAAAAGCACATAGGGCTAAAGGAGGTGCTAGAGATAAAATTCA
TTCCTTAAAAGGAGAATTTAGCCTAAGTATTAACGATAAAAAACTACAATTCTTACAGAAATTAAGAGATGAAGCGCATC
GTTTTGCTATCAGCTTTCATCAAAATACTAAGAAAAAACAGGACTTGAATAGTTCTAAGCTTGTAAATTTAGGACTTAGT
TCAGGGGTTATACAAAAACTTTTAGCGTATTATGGAAATTTTGAATCTATATATAAGGCTGATTTTAAAGATCTTGCAAT
GCTTGTAGGCAAGAAAGTGGCACAAAAGATAAAGGAAAATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-236)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(383-537)

GIY-YIG catalytic domain (GIY-YIG)

(18-99)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

45.96

99

0.455