Detailed information NTG0868673

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RAM30_RS07005
• Genome accession: NZ_CP132371
• Coordinates: 1398292..1399335 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain UNC_SA38
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1393292..1404335

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RAM30_RS06975 (RAM30_06970)	-	1393713..1394969 (-)	1257	WP_001795108.1	aminopeptidase	-
RAM30_RS06980 (RAM30_06975)	-	1394972..1395172 (-)	201	WP_000180460.1	DUF1128 family protein	-
RAM30_RS06985 (RAM30_06980)	-	1395319..1395783 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RAM30_RS06990 (RAM30_06985)	-	1395790..1396065 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
RAM30_RS06995 (RAM30_06990)	-	1396343..1397560 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
RAM30_RS07000 (RAM30_06995)	vraR	1397673..1398302 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
RAM30_RS07005 (RAM30_07000)	vraS	1398292..1399335 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RAM30_RS07010 (RAM30_07005)	liaF	1399332..1400033 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
RAM30_RS07015 (RAM30_07010)	-	1400048..1400434 (-)	387	WP_001110179.1	hypothetical protein	-
RAM30_RS07020 (RAM30_07015)	map	1400651..1401409 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RAM30_RS07025 (RAM30_07020)	-	1401940..1402926 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
RAM30_RS07030 (RAM30_07025)	-	1403357..1403770 (-)	414	WP_001557448.1	hypothetical protein	-
RAM30_RS07035 (RAM30_07030)	-	1403799..1403909 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=868673 RAM30_RS07005 WP_001017131.1 1398292..1399335(-) (vraS) [Staphylococcus aureus strain UNC_SA38]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=868673 RAM30_RS07005 WP_001017131.1 1398292..1399335(-) (vraS) [Staphylococcus aureus strain UNC_SA38]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1