Detailed information NTG0868600

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RAM29_RS13355
• Genome accession: NZ_CP132367
• Coordinates: 2694435..2695478 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain UNC_SA48
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2689435..2700478

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RAM29_RS13325 (RAM29_13315)	-	2689861..2689971 (+)	111	WP_001790257.1	hypothetical protein	-
RAM29_RS13330 (RAM29_13320)	-	2690000..2690413 (+)	414	WP_001557448.1	hypothetical protein	-
RAM29_RS13335 (RAM29_13325)	-	2690844..2691830 (-)	987	WP_000999717.1	aromatic acid exporter family protein	-
RAM29_RS13340 (RAM29_13330)	map	2692361..2693119 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RAM29_RS13345 (RAM29_13335)	-	2693336..2693722 (+)	387	WP_001110179.1	hypothetical protein	-
RAM29_RS13350 (RAM29_13340)	liaF	2693737..2694438 (+)	702	WP_001558031.1	cell wall-active antibiotics response protein LiaF	-
RAM29_RS13355 (RAM29_13345)	vraS	2694435..2695478 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RAM29_RS13360 (RAM29_13350)	vraR	2695468..2696097 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
RAM29_RS13365 (RAM29_13355)	-	2696210..2697427 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
RAM29_RS13370 (RAM29_13360)	-	2697705..2697980 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
RAM29_RS13375 (RAM29_13365)	-	2697987..2698451 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RAM29_RS13380 (RAM29_13370)	-	2698598..2698798 (+)	201	WP_000180460.1	DUF1128 family protein	-
RAM29_RS13385 (RAM29_13375)	-	2698801..2700057 (+)	1257	WP_001795108.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=868600 RAM29_RS13355 WP_001017131.1 2694435..2695478(+) (vraS) [Staphylococcus aureus strain UNC_SA48]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=868600 RAM29_RS13355 WP_001017131.1 2694435..2695478(+) (vraS) [Staphylococcus aureus strain UNC_SA48]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1