Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   RAM32_RS03745 Genome accession   NZ_CP132361
Coordinates   756031..756705 (+) Length   224 a.a.
NCBI ID   WP_000866106.1    Uniprot ID   -
Organism   Staphylococcus aureus strain UNC_SA56     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 750817..769318 756031..756705 within 0


Gene organization within MGE regions


Location: 750817..769318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RAM32_RS03725 (RAM32_03720) - 750817..751662 (+) 846 WP_000733283.1 BlaZ family penicillin-hydrolyzing class A beta-lactamase PC1 -
  RAM32_RS03730 (RAM32_03725) - 752279..753178 (-) 900 WP_153157951.1 Mph(C) family macrolide 2'-phosphotransferase -
  RAM32_RS03735 (RAM32_03730) msr(A) 753277..754743 (-) 1467 WP_000438874.1 ABC-F type ribosomal protection protein Msr(A) -
  RAM32_RS03740 (RAM32_03735) - 755217..755891 (+) 675 WP_001105960.1 IS6 family transposase -
  RAM32_RS03745 (RAM32_03740) braR 756031..756705 (+) 675 WP_000866106.1 response regulator transcription factor Regulator
  RAM32_RS03750 (RAM32_03745) - 756702..757583 (+) 882 Protein_734 sensor histidine kinase -
  RAM32_RS03755 (RAM32_03750) - 757699..758628 (+) 930 WP_000793446.1 ABC transporter ATP-binding protein -
  RAM32_RS03760 (RAM32_03755) - 758621..759358 (+) 738 WP_000369394.1 ABC transporter permease -
  RAM32_RS03765 (RAM32_03760) - 759372..759560 (+) 189 Protein_737 undecaprenyl-diphosphate phosphatase -
  RAM32_RS03770 (RAM32_03765) - 759605..760279 (+) 675 WP_001105960.1 IS6 family transposase -
  RAM32_RS03775 (RAM32_03770) - 760420..761055 (+) 636 Protein_739 aminoglycoside 6-adenylyltransferase -
  RAM32_RS03780 (RAM32_03775) sat4 761052..761585 (+) 534 WP_031794236.1 streptothricin N-acetyltransferase Sat4 -
  RAM32_RS03785 (RAM32_03780) aph(3')-IIIa 761678..762472 (+) 795 WP_001096887.1 aminoglycoside O-phosphotransferase APH(3')-IIIa -
  RAM32_RS03790 (RAM32_03785) - 762748..762879 (+) 132 Protein_742 HTH domain-containing protein -
  RAM32_RS03795 (RAM32_03790) - 762955..763700 (+) 746 Protein_743 helix-turn-helix transcriptional regulator -
  RAM32_RS03800 (RAM32_03795) - 763811..764470 (+) 660 WP_000802831.1 dihydrofolate reductase family protein -
  RAM32_RS03805 (RAM32_03800) - 764978..765652 (-) 675 WP_001105960.1 IS6 family transposase -
  RAM32_RS03810 (RAM32_03805) mobV 765682..766881 (-) 1200 WP_001829561.1 MobV family relaxase -
  RAM32_RS03815 (RAM32_03810) tet(K) 767068..768447 (-) 1380 WP_000492283.1 tetracycline efflux MFS transporter Tet(K) -
  RAM32_RS03820 (RAM32_03815) - 768644..769318 (+) 675 WP_001105986.1 IS6-like element IS257 family transposase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25839.93 Da        Isoelectric Point: 4.9884

>NTDB_id=868435 RAM32_RS03745 WP_000866106.1 756031..756705(+) (braR) [Staphylococcus aureus strain UNC_SA56]
MKVLIVEDDLVIGKMLAEELKKWQLEPILIEGFNHVMDAFNTNAPELVLLDINLPAFNGYHWCQEIRKVSTVPIIFISSR
NDSMDQVMAMQMGADDFIEKPFNMTVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAAKLKFNEETIDLTHTELQIMH
SLFQNKGKFVSRNALIEKCWESEHFIDDNTLAVNITRLRKKLQKLGLTDFIETKKNVGYRVGDV

Nucleotide


Download         Length: 675 bp        

>NTDB_id=868435 RAM32_RS03745 WP_000866106.1 756031..756705(+) (braR) [Staphylococcus aureus strain UNC_SA56]
ATGAAAGTATTAATCGTAGAGGATGACTTAGTTATCGGGAAGATGCTTGCTGAAGAGCTCAAGAAGTGGCAGCTAGAACC
GATCTTAATAGAAGGTTTCAATCATGTAATGGATGCCTTCAACACGAATGCACCGGAACTTGTGTTACTCGATATTAATT
TACCTGCCTTCAATGGTTATCACTGGTGTCAGGAGATTCGTAAAGTTTCTACTGTACCGATTATATTTATTAGTTCGCGT
AACGACAGTATGGATCAAGTAATGGCGATGCAGATGGGTGCGGATGATTTCATTGAGAAGCCATTTAATATGACTGTTAC
AATTACTAAGATTCAAGCACTATTACGCCGCACGTATGATTTCACCACTCAAGTTAATAATTTAACAGTAGATGATTGCG
AGTTACTACTTGATGCAGCAAAGCTTAAATTTAATGAAGAAACCATAGACCTGACACACACTGAATTGCAAATCATGCAT
AGCTTATTCCAGAACAAGGGCAAATTCGTCAGTCGTAATGCGTTAATCGAAAAATGCTGGGAATCAGAACACTTCATTGA
TGACAATACGCTTGCTGTCAACATTACACGTTTACGCAAAAAGCTACAAAAACTAGGACTTACAGATTTTATCGAAACGA
AGAAAAATGTCGGATATCGTGTAGGTGACGTATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

66.516

98.661

0.656