Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   WHP72_RS06685 Genome accession   NZ_CP148184
Coordinates   1270789..1272597 (-) Length   602 a.a.
NCBI ID   WP_063668024.1    Uniprot ID   -
Organism   Campylobacter jejuni strain Z1323CCJ0088     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1265789..1277597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHP72_RS06660 (WHP72_06660) - 1265919..1267118 (+) 1200 WP_283795193.1 MFS transporter -
  WHP72_RS06665 (WHP72_06665) ciaC 1267174..1267494 (+) 321 WP_002860457.1 invasion antigen CiaC -
  WHP72_RS06670 (WHP72_06670) hemE 1267678..1268700 (+) 1023 WP_002859305.1 uroporphyrinogen decarboxylase -
  WHP72_RS06675 (WHP72_06675) - 1268697..1269599 (+) 903 WP_002860459.1 radical SAM protein -
  WHP72_RS06680 (WHP72_06680) - 1269596..1270792 (-) 1197 WP_060809622.1 hypothetical protein -
  WHP72_RS06685 (WHP72_06685) uvrC 1270789..1272597 (-) 1809 WP_063668024.1 excinuclease ABC subunit UvrC Machinery gene
  WHP72_RS06690 (WHP72_06690) - 1272590..1273084 (-) 495 WP_002868551.1 hypothetical protein -
  WHP72_RS06695 (WHP72_06695) guaA 1273223..1274758 (+) 1536 WP_063668023.1 glutamine-hydrolyzing GMP synthase -
  WHP72_RS06700 (WHP72_06700) - 1274844..1276304 (+) 1461 WP_002867356.1 hypothetical protein -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 70022.24 Da        Isoelectric Point: 9.3818

>NTDB_id=867335 WHP72_RS06685 WP_063668024.1 1270789..1272597(-) (uvrC) [Campylobacter jejuni strain Z1323CCJ0088]
MIKENLENELKTLPNSTGVYQYFNQEGKLLYVGKAKNLKNRVRSYFAFTPNLHANPRNSLRIQKMIEETVHLEFIATNSE
ADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFEEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQK
ASCKSRCIFYQISRCLAPCDKLISKEKYLEILDEAIHALLNPSVLLKNLEKQMLVLAQNENYEEAAKVRDQIAMIKDLEV
KVEIDIAKLEDFEVFALAFENSMLSTLRFVVQNGKIISANSKITPIKNDIQWDQNEIYKQLILENFSMDIPLLANVIYVY
EEFEDRVLLEEILSQRFDKKISIKIPKIGEKRRICDLAFQNALLNIEKEQKNHDFTIQKELKFYFELENLPNDIEIFDNS
HLQGVANVGAMVTYRINSWDKSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKALLDLAKEIIVSSGAN
VDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLKSSKLANLGLS
SGVIQKLLAYYGNFESIYKADFKDLIMLVGRKAAQKIKENLI

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=867335 WHP72_RS06685 WP_063668024.1 1270789..1272597(-) (uvrC) [Campylobacter jejuni strain Z1323CCJ0088]
TTGATTAAAGAGAATTTAGAAAATGAGTTAAAAACTCTTCCTAATAGTACTGGCGTTTATCAATACTTCAATCAAGAAGG
AAAGCTTTTATATGTAGGCAAGGCTAAAAATCTTAAAAATCGTGTTAGATCTTATTTTGCTTTTACTCCAAATTTACATG
CAAATCCAAGAAATTCTTTAAGAATTCAAAAAATGATTGAAGAAACAGTGCATTTGGAATTTATTGCTACTAATTCAGAG
GCTGATGCTTTGATTTTAGAAAATTCTTTTATCAAACAACTGCATCCAAAATATAATATTTTGCTAAGAGATGATAAAAC
TTATCCTTATATTTATGTGGATTTTGAAGAAGAATTTCCACGCTTTGAGATCACTAGAAAATTAGTAAAAAAAAGCAAAA
TTAAATATTTTGGCCCTTTTTTTAAAGGCGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCTTTAAAGCAAAAA
GCAAGTTGTAAATCCCGTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCGCCTTGTGATAAACTCATCAGCAAAGAAAA
ATACCTTGAAATTTTAGATGAGGCTATACACGCACTTTTAAATCCTAGTGTTTTGCTTAAAAACTTAGAAAAACAAATGC
TTGTTTTAGCACAAAATGAAAATTACGAAGAAGCAGCTAAAGTAAGAGATCAGATTGCAATGATTAAAGATTTGGAAGTT
AAGGTTGAAATAGATATTGCAAAATTAGAAGATTTTGAAGTATTTGCTTTAGCTTTTGAAAATTCCATGCTTTCAACCTT
GCGTTTTGTGGTGCAAAATGGAAAAATTATCAGTGCAAATTCTAAGATTACTCCTATAAAAAATGATATACAATGGGATC
AAAATGAAATTTATAAGCAACTGATTTTAGAAAATTTTAGCATGGATATTCCTTTGCTTGCAAATGTTATTTATGTTTAT
GAAGAATTTGAAGATAGAGTGCTTTTAGAAGAAATTTTAAGCCAAAGGTTTGATAAAAAAATCAGTATTAAAATCCCTAA
AATAGGAGAAAAAAGAAGAATTTGTGATTTGGCTTTTCAAAATGCCCTTTTAAATATAGAAAAAGAGCAAAAAAATCATG
ATTTTACTATACAAAAAGAATTAAAGTTTTATTTTGAGCTTGAAAATTTACCAAATGATATAGAAATTTTTGACAATTCT
CATTTGCAAGGCGTGGCAAATGTTGGAGCTATGGTAACTTATAGAATAAATTCTTGGGATAAGTCAAAATATAGAAAATT
TCATTTAAAACATAAAAATGACTATGATCAAATGCGTGAAGTTTTAACGCGTAGGGCTTTGGACTTTGATAAAATACCTC
CTCCTGATTTATGGCTTATAGATGGGGGAAAGGCTTTGCTTGATTTGGCTAAAGAAATCATTGTAAGTAGTGGGGCAAAT
GTCGATATTTTAGCTATTTCAAAAGAAAAAATCGATGCAAAAGCACATAGAGCTAAAGGGGGTGCTAAGGATAAAATTCA
TTCCTTAAAAGGAGAATTTAGTCTAAGCATTAACGATAAAAAACTACAATTCTTACAGAAATTAAGAGATGAAGCACACC
GTTTTGCTATCAGCTTTCATCAAAATACTAAGAAAAAACAGGACTTGAAAAGTTCTAAGCTTGCAAATTTAGGACTTAGT
TCAGGGGTTATACAAAAACTTTTAGCGTATTATGGAAATTTTGAATCTATATATAAGGCTGATTTTAAAGATCTTATAAT
GCTTGTAGGCAGGAAAGCGGCGCAAAAGATAAAGGAAAATTTGATTTGA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-537)

UvrB/uvrC motif (UVR)

(205-237)

GIY-YIG catalytic domain (GIY-YIG)

(18-99)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

47.079

96.678

0.455