Detailed information NTG0866858

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QFX47_RS09570
• Genome accession: NZ_CP132033
• Coordinates: 1939936..1940979 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 2.1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1934936..1945979

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QFX47_RS09540	-	1935358..1936614 (-)	1257	WP_001789555.1	aminopeptidase	-
QFX47_RS09545	-	1936617..1936817 (-)	201	WP_000180460.1	DUF1128 family protein	-
QFX47_RS09550	-	1936964..1937428 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QFX47_RS09555	-	1937435..1937710 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QFX47_RS09560	-	1937988..1939205 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
QFX47_RS09565	vraR	1939317..1939946 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QFX47_RS09570	vraS	1939936..1940979 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QFX47_RS09575	liaF	1940976..1941677 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QFX47_RS09580	-	1941692..1942078 (-)	387	WP_001110179.1	hypothetical protein	-
QFX47_RS09585	map	1942295..1943053 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QFX47_RS09590	-	1943643..1944629 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
QFX47_RS09595	-	1945060..1945473 (-)	414	WP_001566709.1	hypothetical protein	-
QFX47_RS09600	-	1945502..1945613 (-)	112	Protein_1855	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=866858 QFX47_RS09570 WP_001017131.1 1939936..1940979(-) (vraS) [Staphylococcus aureus strain 2.1]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=866858 QFX47_RS09570 WP_001017131.1 1939936..1940979(-) (vraS) [Staphylococcus aureus strain 2.1]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1