Detailed information NTG0866789

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QFX53_RS04270
• Genome accession: NZ_CP132031
• Coordinates: 825080..826123 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 2.3a
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 820080..831123

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QFX53_RS04240	-	820446..820557 (+)	112	Protein_833	hypothetical protein	-
QFX53_RS04245	-	820586..820999 (+)	414	WP_001566709.1	hypothetical protein	-
QFX53_RS04250	-	821430..822416 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
QFX53_RS04255	map	823006..823764 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QFX53_RS04260	-	823981..824367 (+)	387	WP_001110179.1	hypothetical protein	-
QFX53_RS04265	liaF	824382..825083 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QFX53_RS04270	vraS	825080..826123 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QFX53_RS04275	vraR	826113..826742 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QFX53_RS04280	-	826854..828071 (-)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
QFX53_RS04285	-	828349..828624 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
QFX53_RS04290	-	828631..829095 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QFX53_RS04295	-	829242..829442 (+)	201	WP_000180460.1	DUF1128 family protein	-
QFX53_RS04300	-	829445..830701 (+)	1257	WP_001789555.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=866789 QFX53_RS04270 WP_001017131.1 825080..826123(+) (vraS) [Staphylococcus aureus strain 2.3a]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=866789 QFX53_RS04270 WP_001017131.1 825080..826123(+) (vraS) [Staphylococcus aureus strain 2.3a]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1