Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WHO18_RS03105 Genome accession   NZ_CP148128
Coordinates   588556..589197 (+) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis isolate FELIX_MS620     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 583556..594197
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHO18_RS03075 ydfE 584751..585374 (-) 624 WP_003243530.1 flavin reductase family protein -
  WHO18_RS03080 ydfF 585464..586144 (+) 681 WP_003244115.1 winged helix-turn-helix domain-containing protein -
  WHO18_RS03085 ydfG 586224..586667 (-) 444 WP_003242768.1 carboxymuconolactone decarboxylase family protein -
  WHO18_RS03090 - 586753..586932 (-) 180 WP_010886421.1 hypothetical protein -
  WHO18_RS03095 - 586929..587072 (-) 144 WP_003243880.1 hypothetical protein -
  WHO18_RS03100 ydfH 587340..588563 (+) 1224 WP_010886422.1 two-component system sensor histidine kinase YdfH -
  WHO18_RS03105 vraR 588556..589197 (+) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  WHO18_RS03110 ydfJ 589313..591487 (+) 2175 WP_003243548.1 MMPL family transporter -
  WHO18_RS03115 cesA 591899..592801 (-) 903 WP_003242638.1 carboxylesterase -
  WHO18_RS03120 ydfK 593003..593692 (-) 690 WP_003242513.1 DUF554 domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=865758 WHO18_RS03105 WP_003244318.1 588556..589197(+) (vraR) [Bacillus subtilis isolate FELIX_MS620]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=865758 WHO18_RS03105 WP_003244318.1 588556..589197(+) (vraR) [Bacillus subtilis isolate FELIX_MS620]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTAGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAAGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCCATCAGAGGAAATGTGCTATTGCAGCCTGATATCCTTAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362