Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   Q7615_RS03445 Genome accession   NZ_CP131718
Coordinates   660137..660643 (+) Length   168 a.a.
NCBI ID   WP_011272049.1    Uniprot ID   Q4QNA7
Organism   Haemophilus influenzae strain 2016S11-301     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 655137..665643
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7615_RS03425 (Q7615_03430) - 655230..655559 (-) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  Q7615_RS03430 (Q7615_03435) - 655728..656573 (-) 846 WP_011272052.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  Q7615_RS03435 (Q7615_03440) - 656646..659240 (-) 2595 WP_011272051.1 penicillin-binding protein 1A -
  Q7615_RS03440 (Q7615_03445) comA 659339..660136 (+) 798 WP_011272050.1 pilus assembly protein PilM Machinery gene
  Q7615_RS03445 (Q7615_03450) comB 660137..660643 (+) 507 WP_011272049.1 competence protein ComB Machinery gene
  Q7615_RS03450 (Q7615_03455) comC 660640..661161 (+) 522 WP_011272048.1 competence protein ComC Machinery gene
  Q7615_RS03455 (Q7615_03460) comD 661158..661571 (+) 414 WP_011272047.1 pilus assembly protein PilP Machinery gene
  Q7615_RS03460 (Q7615_03465) comE 661581..662918 (+) 1338 WP_011272046.1 type IV pilus secretin PilQ Machinery gene
  Q7615_RS03465 (Q7615_03470) - 662931..663617 (+) 687 WP_011272045.1 ComF family protein -
  Q7615_RS03470 (Q7615_03475) nfuA 663693..664289 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  Q7615_RS03475 (Q7615_03480) nudC 664356..665150 (+) 795 WP_005686893.1 NAD(+) diphosphatase -

Sequence

Protein


Download         Length: 168 a.a.        Molecular weight: 19697.54 Da        Isoelectric Point: 7.4684

>NTDB_id=864643 Q7615_RS03445 WP_011272049.1 660137..660643(+) (comB) [Haemophilus influenzae strain 2016S11-301]
MSMNLLPWRTYQHQKRLRRLAFYIALFILLAINLMLAFSNLIEQQKQNLQAQQTSFEQLNQQLHKTTMQIDQLRSAVKVG
EVLTSIPNEQVKKSLQQLSELPFQQGELNKFKQDANNLSLEGNAQDQTEFELIHQFLKKHFPNVKLSQVQPEQDTLFFHF
DVEQGAEK

Nucleotide


Download         Length: 507 bp        

>NTDB_id=864643 Q7615_RS03445 WP_011272049.1 660137..660643(+) (comB) [Haemophilus influenzae strain 2016S11-301]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAAGCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAATGTTGGCTTTTAGCAATTTGATTGAACAACAGAAACAAAATTTGCAAGCGCAGCAAA
CATCTTTTGAACAACTTAATCAGCAACTTCACAAAACTACCATGCAAATTGATCAGTTACGCAGTGCGGTGAAAGTTGGT
GAAGTTTTGACATCTATTCCCAACGAGCAAGTAAAAAAGAGTTTACAACAGCTAAGTGAATTACCTTTTCAACAAGGAGA
ACTGAATAAATTTAAACAAGATGCCAATAACTTAAGTTTGGAAGGTAACGCGCAAGATCAAACAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGTCAGGTTCAACCTGAACAAGATACATTGTTTTTTCACTTT
GATGTGGAACAAGGGGCGGAAAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QNA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae 86-028NP

100

100

1
  comB Haemophilus influenzae Rd KW20

98.81

100

0.988