Detailed information NTG0864530

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: Q7618_RS09570
• Genome accession: NZ_CP131715
• Coordinates: 1854945..1855982 (-)
• Length: 345 a.a.
• NCBI ID: WP_001813016.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2006C08-243
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1849945..1860982

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7618_RS09545 (Q7618_09520)	-	1850684..1852015 (-)	1332	WP_000390042.1	hemolysin family protein	-
Q7618_RS09550 (Q7618_09525)	endA	1852306..1853130 (-)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
Q7618_RS09555 (Q7618_09530)	-	1853169..1853357 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
Q7618_RS09560 (Q7618_09535)	murA	1853350..1854633 (-)	1284	WP_000358032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
Q7618_RS09565 (Q7618_09540)	-	1854657..1854887 (-)	231	WP_000250390.1	DUF1146 family protein	-
Q7618_RS09570 (Q7618_09545)	sepM	1854945..1855982 (-)	1038	WP_001813016.1	SepM family pheromone-processing serine protease	Regulator
Q7618_RS09575 (Q7618_09550)	coaD	1855966..1856454 (-)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
Q7618_RS09580 (Q7618_09555)	rsmD	1856444..1856983 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
Q7618_RS09585 (Q7618_09560)	asnA	1857048..1858040 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
Q7618_RS09590 (Q7618_09565)	-	1858152..1858835 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
Q7618_RS09595 (Q7618_09570)	-	1858891..1859631 (-)	741	WP_000152679.1	RNA methyltransferase	-
Q7618_RS09600 (Q7618_09575)	-	1859665..1859943 (+)	279	WP_001174614.1	acylphosphatase	-
Q7618_RS09605 (Q7618_09580)	yidC	1860021..1860947 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=864530 Q7618_RS09570 WP_001813016.1 1854945..1855982(-) (sepM) [Streptococcus pneumoniae strain 2006C08-243]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIDLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=864530 Q7618_RS09570 WP_001813016.1 1854945..1855982(-) (sepM) [Streptococcus pneumoniae strain 2006C08-243]
ATGAAAAAAAAGATTAGATGGCCTTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGAAATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGACTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588