Detailed information NTG0864451

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: Q7619_RS09605
• Genome accession: NZ_CP131714
• Coordinates: 1862924..1863961 (-)
• Length: 345 a.a.
• NCBI ID: WP_001813016.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2008C04-309
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1857924..1868961

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7619_RS09580 (Q7619_09550)	-	1858663..1859994 (-)	1332	WP_000390042.1	hemolysin family protein	-
Q7619_RS09585 (Q7619_09555)	endA	1860285..1861109 (-)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
Q7619_RS09590 (Q7619_09560)	-	1861148..1861336 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
Q7619_RS09595 (Q7619_09565)	murA	1861329..1862612 (-)	1284	WP_000358032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
Q7619_RS09600 (Q7619_09570)	-	1862636..1862866 (-)	231	WP_000250390.1	DUF1146 family protein	-
Q7619_RS09605 (Q7619_09575)	sepM	1862924..1863961 (-)	1038	WP_001813016.1	SepM family pheromone-processing serine protease	Regulator
Q7619_RS09610 (Q7619_09580)	coaD	1863945..1864433 (-)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
Q7619_RS09615 (Q7619_09585)	rsmD	1864423..1864962 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
Q7619_RS09620 (Q7619_09590)	asnA	1865027..1866019 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
Q7619_RS09625 (Q7619_09595)	-	1866131..1866814 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
Q7619_RS09630 (Q7619_09600)	-	1866870..1867610 (-)	741	WP_000152679.1	RNA methyltransferase	-
Q7619_RS09635 (Q7619_09605)	-	1867644..1867922 (+)	279	WP_001174614.1	acylphosphatase	-
Q7619_RS09640 (Q7619_09610)	yidC	1868000..1868926 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=864451 Q7619_RS09605 WP_001813016.1 1862924..1863961(-) (sepM) [Streptococcus pneumoniae strain 2008C04-309]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIDLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=864451 Q7619_RS09605 WP_001813016.1 1862924..1863961(-) (sepM) [Streptococcus pneumoniae strain 2008C04-309]
ATGAAAAAAAAGATTAGATGGCCTTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGAAATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGACTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588