Detailed information NTG0864372

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: Q7620_RS09595
• Genome accession: NZ_CP131713
• Coordinates: 1862085..1863122 (-)
• Length: 345 a.a.
• NCBI ID: WP_001813016.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2008C09-276
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1857085..1868122

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7620_RS09570 (Q7620_09540)	-	1857824..1859155 (-)	1332	WP_000390042.1	hemolysin family protein	-
Q7620_RS09575 (Q7620_09545)	endA	1859446..1860270 (-)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
Q7620_RS09580 (Q7620_09550)	-	1860309..1860497 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
Q7620_RS09585 (Q7620_09555)	murA	1860490..1861773 (-)	1284	WP_000358032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
Q7620_RS09590 (Q7620_09560)	-	1861797..1862027 (-)	231	WP_000250390.1	DUF1146 family protein	-
Q7620_RS09595 (Q7620_09565)	sepM	1862085..1863122 (-)	1038	WP_001813016.1	SepM family pheromone-processing serine protease	Regulator
Q7620_RS09600 (Q7620_09570)	coaD	1863106..1863594 (-)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
Q7620_RS09605 (Q7620_09575)	rsmD	1863584..1864123 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
Q7620_RS09610 (Q7620_09580)	asnA	1864188..1865180 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
Q7620_RS09615 (Q7620_09585)	-	1865292..1865975 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
Q7620_RS09620 (Q7620_09590)	-	1866031..1866771 (-)	741	WP_000152679.1	RNA methyltransferase	-
Q7620_RS09625 (Q7620_09595)	-	1866805..1867083 (+)	279	WP_001174614.1	acylphosphatase	-
Q7620_RS09630 (Q7620_09600)	yidC	1867161..1868087 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=864372 Q7620_RS09595 WP_001813016.1 1862085..1863122(-) (sepM) [Streptococcus pneumoniae strain 2008C09-276]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIDLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=864372 Q7620_RS09595 WP_001813016.1 1862085..1863122(-) (sepM) [Streptococcus pneumoniae strain 2008C09-276]
ATGAAAAAAAAGATTAGATGGCCTTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGAAATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGACTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588