Detailed information NTG0864293

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: Q7621_RS09525
• Genome accession: NZ_CP131712
• Coordinates: 1919415..1920452 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727280.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2008C09-280
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1914415..1925452

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7621_RS09500 (Q7621_09495)	-	1915216..1916547 (-)	1332	WP_000390046.1	hemolysin family protein	-
Q7621_RS09505 (Q7621_09500)	endA	1916776..1917600 (-)	825	WP_001036779.1	DNA-entry nuclease EndA	Machinery gene
Q7621_RS09510 (Q7621_09505)	-	1917639..1917827 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
Q7621_RS09515 (Q7621_09510)	murA	1917820..1919103 (-)	1284	WP_000358033.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
Q7621_RS09520 (Q7621_09515)	-	1919127..1919357 (-)	231	WP_000615437.1	DUF1146 family protein	-
Q7621_RS09525 (Q7621_09520)	sepM	1919415..1920452 (-)	1038	WP_000727280.1	SepM family pheromone-processing serine protease	Regulator
Q7621_RS09530 (Q7621_09525)	coaD	1920436..1920924 (-)	489	WP_001280766.1	pantetheine-phosphate adenylyltransferase	-
Q7621_RS09535 (Q7621_09530)	rsmD	1920914..1921453 (-)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
Q7621_RS09540 (Q7621_09535)	asnA	1921518..1922510 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
Q7621_RS09545 (Q7621_09540)	-	1922622..1923305 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
Q7621_RS09550 (Q7621_09545)	-	1923361..1924101 (-)	741	WP_000152701.1	RNA methyltransferase	-
Q7621_RS09555 (Q7621_09550)	-	1924135..1924413 (+)	279	WP_001174613.1	acylphosphatase	-
Q7621_RS09560 (Q7621_09555)	yidC	1924491..1925417 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37567.60 Da
• Isoelectric Point: 5.0724

>NTDB_id=864293 Q7621_RS09525 WP_000727280.1 1919415..1920452(-) (sepM) [Streptococcus pneumoniae strain 2008C09-280]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=864293 Q7621_RS09525 WP_000727280.1 1919415..1920452(-) (sepM) [Streptococcus pneumoniae strain 2008C09-280]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591