Detailed information NTG0864216

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: Q7622_RS09220
• Genome accession: NZ_CP131711
• Coordinates: 1806580..1807617 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727280.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2014C08-275
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1801580..1812617

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7622_RS09195 (Q7622_09165)	-	1802319..1803650 (-)	1332	WP_000390039.1	hemolysin family protein	-
Q7622_RS09200 (Q7622_09170)	endA	1803941..1804765 (-)	825	WP_001036785.1	DNA-entry nuclease EndA	Machinery gene
Q7622_RS09205 (Q7622_09175)	-	1804804..1804992 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
Q7622_RS09210 (Q7622_09180)	murA	1804985..1806268 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
Q7622_RS09215 (Q7622_09185)	-	1806292..1806522 (-)	231	WP_000615437.1	DUF1146 family protein	-
Q7622_RS09220 (Q7622_09190)	sepM	1806580..1807617 (-)	1038	WP_000727280.1	SepM family pheromone-processing serine protease	Regulator
Q7622_RS09225 (Q7622_09195)	coaD	1807601..1808089 (-)	489	WP_001280766.1	pantetheine-phosphate adenylyltransferase	-
Q7622_RS09230 (Q7622_09200)	rsmD	1808079..1808618 (-)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
Q7622_RS09235 (Q7622_09205)	asnA	1808683..1809675 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
Q7622_RS09240 (Q7622_09210)	-	1809787..1810470 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
Q7622_RS09245 (Q7622_09215)	-	1810526..1811266 (-)	741	WP_000152701.1	RNA methyltransferase	-
Q7622_RS09250 (Q7622_09220)	-	1811300..1811578 (+)	279	WP_001174613.1	acylphosphatase	-
Q7622_RS09255 (Q7622_09225)	yidC	1811656..1812582 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37567.60 Da
• Isoelectric Point: 5.0724

>NTDB_id=864216 Q7622_RS09220 WP_000727280.1 1806580..1807617(-) (sepM) [Streptococcus pneumoniae strain 2014C08-275]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=864216 Q7622_RS09220 WP_000727280.1 1806580..1807617(-) (sepM) [Streptococcus pneumoniae strain 2014C08-275]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591