Detailed information NTG0864204

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: Q7622_RS08555
• Genome accession: NZ_CP131711
• Coordinates: 1695026..1696093 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159553.1
• Uniprot ID: A0A0T8CF10
• Organism: Streptococcus pneumoniae strain 2014C08-275
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1690026..1701093

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7622_RS08535 (Q7622_08505)	-	1690975..1692005 (-)	1031	Protein_1689	IS630 family transposase	-
Q7622_RS08540 (Q7622_08510)	-	1692290..1693636 (+)	1347	WP_001821265.1	IS1380-like element ISSpn5 family transposase	-
Q7622_RS08545 (Q7622_08515)	-	1693829..1694014 (+)	186	Protein_1691	transposase	-
Q7622_RS08550 (Q7622_08520)	amiF	1694089..1695015 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
Q7622_RS08555 (Q7622_08525)	amiE	1695026..1696093 (-)	1068	WP_000159553.1	ABC transporter ATP-binding protein	Regulator
Q7622_RS08560 (Q7622_08530)	amiD	1696102..1697028 (-)	927	WP_000103702.1	oligopeptide ABC transporter permease OppC	Regulator
Q7622_RS08565 (Q7622_08535)	amiC	1697028..1698524 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
Q7622_RS08570 (Q7622_08540)	amiA3	1698591..1700570 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39437.04 Da
• Isoelectric Point: 4.8002

>NTDB_id=864204 Q7622_RS08555 WP_000159553.1 1695026..1696093(-) (amiE) [Streptococcus pneumoniae strain 2014C08-275]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=864204 Q7622_RS08555 WP_000159553.1 1695026..1696093(-) (amiE) [Streptococcus pneumoniae strain 2014C08-275]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTTGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0T8CF10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.761	100	0.868
amiE	Streptococcus thermophilus LMD-9	86.761	100	0.868
oppD	Streptococcus mutans UA159	54.545	99.155	0.541