Detailed information NTG0864140

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: Q7623_RS09605
• Genome accession: NZ_CP131710
• Coordinates: 1855685..1856722 (-)
• Length: 345 a.a.
• NCBI ID: WP_001813016.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2014S11-203
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1850685..1861722

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7623_RS09580 (Q7623_09545)	-	1851424..1852755 (-)	1332	WP_000390042.1	hemolysin family protein	-
Q7623_RS09585 (Q7623_09550)	endA	1853046..1853870 (-)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
Q7623_RS09590 (Q7623_09555)	-	1853909..1854097 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
Q7623_RS09595 (Q7623_09560)	murA	1854090..1855373 (-)	1284	WP_000358032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
Q7623_RS09600 (Q7623_09565)	-	1855397..1855627 (-)	231	WP_000250390.1	DUF1146 family protein	-
Q7623_RS09605 (Q7623_09570)	sepM	1855685..1856722 (-)	1038	WP_001813016.1	SepM family pheromone-processing serine protease	Regulator
Q7623_RS09610 (Q7623_09575)	coaD	1856706..1857194 (-)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
Q7623_RS09615 (Q7623_09580)	rsmD	1857184..1857723 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
Q7623_RS09620 (Q7623_09585)	asnA	1857788..1858780 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
Q7623_RS09625 (Q7623_09590)	-	1858892..1859575 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
Q7623_RS09630 (Q7623_09595)	-	1859631..1860371 (-)	741	WP_000152679.1	RNA methyltransferase	-
Q7623_RS09635 (Q7623_09600)	-	1860405..1860683 (+)	279	WP_001174614.1	acylphosphatase	-
Q7623_RS09640 (Q7623_09605)	yidC	1860761..1861687 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=864140 Q7623_RS09605 WP_001813016.1 1855685..1856722(-) (sepM) [Streptococcus pneumoniae strain 2014S11-203]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIDLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=864140 Q7623_RS09605 WP_001813016.1 1855685..1856722(-) (sepM) [Streptococcus pneumoniae strain 2014S11-203]
ATGAAAAAAAAGATTAGATGGCCTTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGAAATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGACTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588