Detailed information NTG0864050

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: Q7624_RS08650
• Genome accession: NZ_CP131709
• Coordinates: 1693111..1694178 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159553.1
• Uniprot ID: A0A0T8CF10
• Organism: Streptococcus pneumoniae strain 2016S11-245
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1688111..1699178

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7624_RS08625 (Q7624_08600)	treR	1688198..1688908 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
Q7624_RS08630 (Q7624_08605)	-	1689065..1690208 (+)	1144	Protein_1708	transposase	-
Q7624_RS08635 (Q7624_08610)	-	1690375..1691721 (+)	1347	WP_001814919.1	IS1380-like element ISSpn5 family transposase	-
Q7624_RS08640 (Q7624_08615)	-	1691914..1692099 (+)	186	Protein_1710	transposase	-
Q7624_RS08645 (Q7624_08620)	amiF	1692174..1693100 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
Q7624_RS08650 (Q7624_08625)	amiE	1693111..1694178 (-)	1068	WP_000159553.1	ABC transporter ATP-binding protein	Regulator
Q7624_RS08655 (Q7624_08630)	amiD	1694187..1695113 (-)	927	WP_000103702.1	oligopeptide ABC transporter permease OppC	Regulator
Q7624_RS08660 (Q7624_08635)	amiC	1695113..1696609 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
Q7624_RS08665 (Q7624_08640)	amiA3	1696676..1698655 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39437.04 Da
• Isoelectric Point: 4.8002

>NTDB_id=864050 Q7624_RS08650 WP_000159553.1 1693111..1694178(-) (amiE) [Streptococcus pneumoniae strain 2016S11-245]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=864050 Q7624_RS08650 WP_000159553.1 1693111..1694178(-) (amiE) [Streptococcus pneumoniae strain 2016S11-245]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTTGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0T8CF10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.761	100	0.868
amiE	Streptococcus thermophilus LMD-9	86.761	100	0.868
oppD	Streptococcus mutans UA159	54.545	99.155	0.541