Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WHL49_RS02980 Genome accession   NZ_CP148103
Coordinates   568849..569490 (+) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis subsp. subtilis isolate FELIX_MS361     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 563849..574490
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHL49_RS02950 ydfE 565044..565667 (-) 624 WP_003243530.1 flavin reductase family protein -
  WHL49_RS02955 ydfF 565757..566437 (+) 681 WP_003244115.1 winged helix-turn-helix domain-containing protein -
  WHL49_RS02960 ydfG 566517..566960 (-) 444 WP_003242768.1 carboxymuconolactone decarboxylase family protein -
  WHL49_RS02965 - 567046..567225 (-) 180 WP_010886421.1 hypothetical protein -
  WHL49_RS02970 - 567222..567365 (-) 144 WP_003243880.1 hypothetical protein -
  WHL49_RS02975 ydfH 567633..568856 (+) 1224 WP_010886422.1 two-component system sensor histidine kinase YdfH -
  WHL49_RS02980 vraR 568849..569490 (+) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  WHL49_RS02985 ydfJ 569606..571780 (+) 2175 WP_003243548.1 MMPL family transporter -
  WHL49_RS02990 cesA 572192..573094 (-) 903 WP_003242638.1 carboxylesterase -
  WHL49_RS02995 ydfK 573296..573985 (-) 690 WP_003242513.1 DUF554 domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=864003 WHL49_RS02980 WP_003244318.1 568849..569490(+) (vraR) [Bacillus subtilis subsp. subtilis isolate FELIX_MS361]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=864003 WHL49_RS02980 WP_003244318.1 568849..569490(+) (vraR) [Bacillus subtilis subsp. subtilis isolate FELIX_MS361]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTAGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAAGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCCATCAGAGGAAATGTGCTATTGCAGCCTGATATCCTTAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362