Detailed information NTG0863909

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: Q7626_RS09305
• Genome accession: NZ_CP131707
• Coordinates: 1833701..1834714 (-)
• Length: 337 a.a.
• NCBI ID: WP_001857085.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2018C08-270
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1828701..1839714

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7626_RS09280 (Q7626_09265)	-	1829440..1830771 (-)	1332	WP_000390044.1	hemolysin family protein	-
Q7626_RS09285 (Q7626_09270)	endA	1831062..1831886 (-)	825	WP_001036785.1	DNA-entry nuclease EndA	Machinery gene
Q7626_RS09290 (Q7626_09275)	-	1831925..1832113 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
Q7626_RS09295 (Q7626_09280)	murA	1832106..1833389 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
Q7626_RS09300 (Q7626_09285)	-	1833413..1833643 (-)	231	WP_000250391.1	DUF1146 family protein	-
Q7626_RS09305 (Q7626_09290)	sepM	1833701..1834714 (-)	1014	WP_001857085.1	SepM family pheromone-processing serine protease	Regulator
Q7626_RS09310 (Q7626_09295)	coaD	1834693..1835211 (-)	519	WP_088792017.1	pantetheine-phosphate adenylyltransferase	-
Q7626_RS09315 (Q7626_09300)	rsmD	1835201..1835740 (-)	540	WP_000691938.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
Q7626_RS09320 (Q7626_09305)	asnA	1835805..1836797 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
Q7626_RS09325 (Q7626_09310)	-	1836910..1837593 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
Q7626_RS09330 (Q7626_09315)	-	1837649..1838389 (-)	741	WP_000152674.1	RNA methyltransferase	-
Q7626_RS09335 (Q7626_09320)	-	1838423..1838701 (+)	279	WP_001174613.1	acylphosphatase	-
Q7626_RS09340 (Q7626_09325)	yidC	1838779..1839705 (+)	927	WP_000835944.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 337 a.a.
• Molecular weight: 36487.21 Da
• Isoelectric Point: 4.6730

>NTDB_id=863909 Q7626_RS09305 WP_001857085.1 1833701..1834714(-) (sepM) [Streptococcus pneumoniae strain 2018C08-270]
MYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQET
TGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTFDSSKDLID
YVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSLAIYTQIAH
PDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKI
VPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1014 bp

>NTDB_id=863909 Q7626_RS09305 WP_001857085.1 1833701..1834714(-) (sepM) [Streptococcus pneumoniae strain 2018C08-270]
TTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCCCTACTATATAGAGGTTCCAGGTGG
TTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTGGTGCCTATCAATTCGTTACGGTTG
GTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACAGATATTCGTAGTGCTCAGGAGACT
ACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAACATCGCAAAATATGGCCAAGTATCA
AGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTTTGAATGTGACGGATAATTCAACCT
TTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTTGATAGTTCCAAAGACTTGATTGAT
TACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGGGCAAACCAAGTCTGCAGAAGGAAA
GATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTACAGAGGTAATCAGCAATGTCCCAA
TTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTAGCTATCTATACTCAAATAGCTCAC
CCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGGTAATGTGGGAGACATTGGAGGTAT
TGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTGATAACCCTGTTAGCGAAGAAGAAC
AAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAAACAATCAAGACGGATATGAAAATC
GTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (122-185)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (223-288)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.423	98.22	0.593