Detailed information NTG0863634

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: Q7635_RS13730
• Genome accession: NZ_CP131670
• Coordinates: 2734647..2735534 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 2004N07-109
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2729647..2740534

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7635_RS13705 (Q7635_13700)	-	2729649..2729741 (+)	93	WP_010956583.1	hypothetical protein	-
Q7635_RS13710 (Q7635_13705)	-	2729849..2730346 (-)	498	WP_001065268.1	glutathione peroxidase	-
Q7635_RS13715 (Q7635_13710)	-	2730356..2730616 (-)	261	WP_001789910.1	hypothetical protein	-
Q7635_RS13720 (Q7635_13715)	-	2731787..2733787 (-)	2001	WP_216734079.1	ABC transporter permease	-
Q7635_RS13725 (Q7635_13720)	-	2733784..2734539 (-)	756	WP_001836721.1	ABC transporter ATP-binding protein	-
Q7635_RS13730 (Q7635_13725)	braS	2734647..2735534 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
Q7635_RS13735 (Q7635_13730)	braR	2735545..2736210 (-)	666	WP_216734086.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
Q7635_RS13740 (Q7635_13735)	-	2736236..2736436 (-)	201	WP_000604727.1	hypothetical protein	-
Q7635_RS13745 (Q7635_13740)	-	2736634..2738058 (+)	1425	WP_000953748.1	alkaline phosphatase	-
Q7635_RS13750 (Q7635_13745)	-	2738129..2738239 (+)	111	Protein_2667	hypothetical protein	-
Q7635_RS13755 (Q7635_13750)	-	2738342..2738797 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
Q7635_RS13760 (Q7635_13755)	-	2739042..2739803 (-)	762	WP_341931179.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=863634 Q7635_RS13730 WP_000143419.1 2734647..2735534(-) (braS) [Staphylococcus aureus strain 2004N07-109]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=863634 Q7635_RS13730 WP_000143419.1 2734647..2735534(-) (braS) [Staphylococcus aureus strain 2004N07-109]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGTTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997