Detailed information NTG0863629

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q7635_RS09755
• Genome accession: NZ_CP131670
• Coordinates: 1975850..1976893 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 2004N07-109
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1970850..1981893

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7635_RS09725 (Q7635_09720)	-	1971272..1972528 (-)	1257	WP_075583716.1	aminopeptidase	-
Q7635_RS09730 (Q7635_09725)	-	1972531..1972731 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q7635_RS09735 (Q7635_09730)	-	1972878..1973342 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q7635_RS09740 (Q7635_09735)	-	1973349..1973624 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q7635_RS09745 (Q7635_09740)	-	1973902..1975119 (+)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
Q7635_RS09750 (Q7635_09745)	vraR	1975231..1975860 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
Q7635_RS09755 (Q7635_09750)	vraS	1975850..1976893 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q7635_RS09760 (Q7635_09755)	liaF	1976890..1977591 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q7635_RS09765 (Q7635_09760)	-	1977606..1977992 (-)	387	WP_001110179.1	hypothetical protein	-
Q7635_RS09770 (Q7635_09765)	map	1978209..1978967 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q7635_RS09775 (Q7635_09770)	-	1979439..1980425 (+)	987	WP_000999718.1	aromatic acid exporter family protein	-
Q7635_RS09780 (Q7635_09775)	-	1980856..1981269 (-)	414	WP_341931250.1	hypothetical protein	-
Q7635_RS09785 (Q7635_09780)	-	1981298..1981408 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=863629 Q7635_RS09755 WP_001017131.1 1975850..1976893(-) (vraS) [Staphylococcus aureus strain 2004N07-109]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=863629 Q7635_RS09755 WP_001017131.1 1975850..1976893(-) (vraS) [Staphylococcus aureus strain 2004N07-109]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1