Detailed information NTG0863590

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: Q7636_RS13445
• Genome accession: NZ_CP131668
• Coordinates: 2695145..2696032 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 2004S09-216
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2690145..2701032

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7636_RS13415 (Q7636_13405)	-	2690164..2690256 (+)	93	WP_010956583.1	hypothetical protein	-
Q7636_RS13420 (Q7636_13410)	-	2690364..2690861 (-)	498	WP_001065268.1	glutathione peroxidase	-
Q7636_RS13425 (Q7636_13415)	-	2690871..2691131 (-)	261	WP_001789910.1	hypothetical protein	-
Q7636_RS13430 (Q7636_13420)	-	2691513..2691626 (-)	114	WP_011447078.1	hypothetical protein	-
Q7636_RS13435 (Q7636_13425)	-	2692285..2694285 (-)	2001	WP_000776751.1	ABC transporter permease	-
Q7636_RS13440 (Q7636_13430)	-	2694282..2695037 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
Q7636_RS13445 (Q7636_13435)	braS	2695145..2696032 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
Q7636_RS13450 (Q7636_13440)	braR	2696043..2696708 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
Q7636_RS13455 (Q7636_13445)	-	2696734..2696934 (-)	201	WP_000604732.1	hypothetical protein	-
Q7636_RS13460 (Q7636_13450)	-	2697132..2698556 (+)	1425	WP_000953744.1	alkaline phosphatase	-
Q7636_RS13465 (Q7636_13455)	-	2698626..2698736 (+)	111	WP_001791296.1	hypothetical protein	-
Q7636_RS13470 (Q7636_13460)	-	2698839..2699294 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
Q7636_RS13475 (Q7636_13465)	-	2699539..2700300 (-)	762	WP_341986378.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=863590 Q7636_RS13445 WP_000143419.1 2695145..2696032(-) (braS) [Staphylococcus aureus strain 2004S09-216]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=863590 Q7636_RS13445 WP_000143419.1 2695145..2696032(-) (braS) [Staphylococcus aureus strain 2004S09-216]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997