Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | Q7637_RS00285 | Genome accession | NZ_CP131665 |
| Coordinates | 62722..64350 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain 2010S01-051 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 57501..101226 | 62722..64350 | within | 0 |
| SCCmec | 44355..65721 | 62722..64350 | within | 0 |
Gene organization within MGE regions
Location: 44355..101226
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| Q7637_RS00190 (Q7637_00190) | mecA | 44355..46364 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| Q7637_RS00195 (Q7637_00195) | mecR1 | 46461..48218 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| Q7637_RS00200 (Q7637_00200) | mecI | 48218..48589 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| Q7637_RS00205 (Q7637_00205) | psm-mec | 48674..48742 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| Q7637_RS00210 (Q7637_00210) | - | 49076..50206 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| Q7637_RS00215 (Q7637_00215) | cstB | 50320..51654 (-) | 1335 | Protein_40 | persulfide dioxygenase-sulfurtransferase CstB | - |
| Q7637_RS00220 (Q7637_00220) | - | 51687..52752 (-) | 1066 | Protein_41 | DsrE/DsrF/DrsH-like family protein | - |
| Q7637_RS00225 (Q7637_00225) | cstR | 52888..53148 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| Q7637_RS00230 (Q7637_00230) | - | 53148..53786 (+) | 639 | Protein_43 | sulfite exporter TauE/SafE family protein | - |
| Q7637_RS00235 (Q7637_00235) | - | 54131..54793 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| Q7637_RS00240 (Q7637_00240) | erm(A) | 55327..56058 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| Q7637_RS00245 (Q7637_00245) | - | 56184..56966 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| Q7637_RS00250 (Q7637_00250) | - | 57117..57494 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| Q7637_RS00255 (Q7637_00255) | - | 57501..59393 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| Q7637_RS00260 (Q7637_00260) | - | 59390..60475 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| Q7637_RS00265 (Q7637_00265) | - | 60594..60911 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| Q7637_RS00270 (Q7637_00270) | - | 60932..61438 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| Q7637_RS00275 (Q7637_00275) | - | 61456..61767 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| Q7637_RS00280 (Q7637_00280) | - | 61854..62204 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| Q7637_RS00285 (Q7637_00285) | ccrB | 62722..64350 (-) | 1629 | WP_001186602.1 | recombinase family protein | Machinery gene |
| Q7637_RS00290 (Q7637_00290) | ccrA | 64372..65721 (-) | 1350 | WP_000815646.1 | recombinase family protein | Machinery gene |
| Q7637_RS00295 (Q7637_00295) | - | 65955..67748 (-) | 1794 | WP_000195100.1 | DUF927 domain-containing protein | - |
| Q7637_RS00300 (Q7637_00300) | - | 67748..68044 (-) | 297 | WP_000273824.1 | single-stranded DNA-binding protein | - |
| Q7637_RS00305 (Q7637_00305) | - | 68237..69283 (-) | 1047 | WP_001060127.1 | hypothetical protein | - |
| Q7637_RS00310 (Q7637_00310) | - | 69534..70675 (-) | 1142 | Protein_59 | IS3-like element ISSau4 family transposase | - |
| Q7637_RS00315 (Q7637_00315) | - | 71186..72112 (-) | 927 | Protein_60 | YfcC family protein | - |
| Q7637_RS00320 (Q7637_00320) | - | 72834..73529 (-) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| Q7637_RS00325 (Q7637_00325) | - | 73504..76173 (-) | 2670 | WP_000446429.1 | sensor histidine kinase KdpD | - |
| Q7637_RS00330 (Q7637_00330) | kdpF | 76340..76420 (+) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| Q7637_RS00335 (Q7637_00335) | kdpA | 76441..78117 (+) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| Q7637_RS00340 (Q7637_00340) | - | 78136..80157 (+) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| Q7637_RS00345 (Q7637_00345) | - | 80173..80730 (+) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| Q7637_RS00350 (Q7637_00350) | - | 81275..82144 (-) | 870 | WP_000626133.1 | hypothetical protein | - |
| Q7637_RS00355 (Q7637_00355) | - | 82154..83050 (-) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| Q7637_RS00360 (Q7637_00360) | - | 84169..84795 (-) | 627 | WP_001176969.1 | hypothetical protein | - |
| Q7637_RS00365 (Q7637_00365) | - | 84910..86418 (+) | 1509 | WP_001001347.1 | protein kinase | - |
| Q7637_RS00370 (Q7637_00370) | - | 86668..86802 (-) | 135 | WP_001790628.1 | hypothetical protein | - |
| Q7637_RS00375 (Q7637_00375) | - | 86766..86858 (+) | 93 | WP_001790000.1 | hypothetical protein | - |
| Q7637_RS00380 (Q7637_00380) | - | 87005..88750 (+) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| Q7637_RS00385 (Q7637_00385) | - | 88848..89203 (-) | 356 | Protein_74 | tRNA-dihydrouridine synthase | - |
| Q7637_RS00390 (Q7637_00390) | - | 89508..89596 (-) | 89 | Protein_75 | hypothetical protein | - |
| Q7637_RS00395 (Q7637_00395) | - | 89694..90449 (-) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| Q7637_RS00400 (Q7637_00400) | cstR | 90449..90709 (-) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| Q7637_RS00405 (Q7637_00405) | cstA | 90846..91910 (+) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| Q7637_RS00410 (Q7637_00410) | cstB | 91941..93275 (+) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| Q7637_RS00415 (Q7637_00415) | sqr | 93294..94487 (+) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| Q7637_RS00420 | - | 94754..94968 (-) | 215 | Protein_81 | universal stress protein | - |
| Q7637_RS00425 (Q7637_00420) | - | 95154..96140 (-) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| Q7637_RS00430 (Q7637_00425) | - | 96449..96652 (+) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| Q7637_RS00435 (Q7637_00430) | - | 96701..96997 (+) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| Q7637_RS00440 (Q7637_00435) | - | 97205..97807 (+) | 603 | WP_000908956.1 | hypothetical protein | - |
| Q7637_RS00445 (Q7637_00440) | - | 98074..101226 (+) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=863505 Q7637_RS00285 WP_001186602.1 62722..64350(-) (ccrB) [Staphylococcus aureus strain 2010S01-051]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=863505 Q7637_RS00285 WP_001186602.1 62722..64350(-) (ccrB) [Staphylococcus aureus strain 2010S01-051]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |