Detailed information NTG0863496

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q7638_RS09905
• Genome accession: NZ_CP131663
• Coordinates: 2004970..2006013 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 2010C06-103
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1999970..2011013

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7638_RS09875 (Q7638_09855)	-	2000391..2001647 (-)	1257	WP_078065149.1	aminopeptidase	-
Q7638_RS09880 (Q7638_09860)	-	2001650..2001850 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q7638_RS09885 (Q7638_09865)	-	2001997..2002461 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q7638_RS09890 (Q7638_09870)	-	2002468..2002743 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q7638_RS09895 (Q7638_09875)	-	2003021..2004238 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
Q7638_RS09900 (Q7638_09880)	vraR	2004351..2004980 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
Q7638_RS09905 (Q7638_09885)	vraS	2004970..2006013 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q7638_RS09910 (Q7638_09890)	liaF	2006010..2006711 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q7638_RS09915 (Q7638_09895)	-	2006726..2007112 (-)	387	WP_001110179.1	hypothetical protein	-
Q7638_RS09920 (Q7638_09900)	map	2007329..2008087 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q7638_RS09925 (Q7638_09905)	-	2008616..2009602 (+)	987	WP_000999708.1	aromatic acid exporter family protein	-
Q7638_RS09930 (Q7638_09910)	-	2010035..2010448 (-)	414	WP_025174552.1	hypothetical protein	-
Q7638_RS09935 (Q7638_09915)	-	2010477..2010587 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=863496 Q7638_RS09905 WP_001017131.1 2004970..2006013(-) (vraS) [Staphylococcus aureus strain 2010C06-103]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=863496 Q7638_RS09905 WP_001017131.1 2004970..2006013(-) (vraS) [Staphylococcus aureus strain 2010C06-103]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1