Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   CPY3401_RS04585 Genome accession   NZ_AP024599
Coordinates   957559..959343 (+) Length   594 a.a.
NCBI ID   WP_221062214.1    Uniprot ID   -
Organism   Helicobacter pylori strain 3401     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 952559..964343
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CPY3401_RS04555 (CPY3401_09260) motB 953220..953987 (+) 768 WP_221062211.1 flagellar motor protein MotB -
  CPY3401_RS04560 (CPY3401_09270) - 953991..954428 (+) 438 WP_001031792.1 hypothetical protein -
  CPY3401_RS04565 (CPY3401_09280) - 954731..956269 (+) 1539 WP_221062212.1 ABC transporter permease/substrate-binding protein -
  CPY3401_RS04570 (CPY3401_09290) - 956273..956914 (+) 642 WP_221062213.1 ABC transporter ATP-binding protein -
  CPY3401_RS04575 - 956926..957105 (-) 180 WP_000468796.1 hypothetical protein -
  CPY3401_RS04580 (CPY3401_09300) - 957097..957558 (+) 462 WP_000437191.1 hypothetical protein -
  CPY3401_RS04585 (CPY3401_09310) uvrC 957559..959343 (+) 1785 WP_221062214.1 excinuclease ABC subunit UvrC Machinery gene
  CPY3401_RS04590 (CPY3401_09320) - 959354..960619 (+) 1266 WP_180400926.1 homoserine dehydrogenase -
  CPY3401_RS04595 (CPY3401_09330) - 960620..960964 (+) 345 WP_001211650.1 YraN family protein -
  CPY3401_RS04600 (CPY3401_09340) trxA 961053..961373 (+) 321 WP_000020199.1 thioredoxin -
  CPY3401_RS04605 (CPY3401_09350) trxB 961379..962314 (+) 936 WP_212790325.1 thioredoxin-disulfide reductase -
  CPY3401_RS04610 (CPY3401_09360) - 962481..963302 (+) 822 WP_221062215.1 glycosyltransferase family 25 protein -
  CPY3401_RS04615 (CPY3401_09370) - 963509..963757 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68889.18 Da        Isoelectric Point: 9.7010

>NTDB_id=86337 CPY3401_RS04585 WP_221062214.1 957559..959343(+) (uvrC) [Helicobacter pylori strain 3401]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIRSYFSVHNNEITPNHRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKYKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDV
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=86337 CPY3401_RS04585 WP_221062214.1 957559..959343(+) (uvrC) [Helicobacter pylori strain 3401]
ATGGCTGATTTGTTGTCCAGTTTAAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAGAAGCTATTTTTCTGTCCACAATAATGAAATCACGCCCA
ATCATCGCACAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAACAACTCAAACCCAAATACAATATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAATATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAATATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGATAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATAGTGGGAACAATAAGGCGGT
ATTAGTGAAGATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGTA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCCAAAGGAGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCTACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAAGGCATA
GGAGAAGCTAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.633

100

0.966

Multiple sequence alignment