Detailed information NTG0863322

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q7642_RS09650
• Genome accession: NZ_CP131652
• Coordinates: 1988289..1989332 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017129.1
• Uniprot ID: A0A0U1MRG1
• Organism: Staphylococcus aureus strain 2008S01-206
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1983289..1994332

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7642_RS09620 (Q7642_09610)	-	1983710..1984966 (-)	1257	WP_001793428.1	aminopeptidase	-
Q7642_RS09625 (Q7642_09615)	-	1984969..1985169 (-)	201	WP_001813025.1	DUF1128 family protein	-
Q7642_RS09630 (Q7642_09620)	-	1985316..1985780 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q7642_RS09635 (Q7642_09625)	-	1985787..1986062 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q7642_RS09640 (Q7642_09630)	-	1986340..1987557 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
Q7642_RS09645 (Q7642_09635)	vraR	1987670..1988299 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
Q7642_RS09650 (Q7642_09640)	vraS	1988289..1989332 (-)	1044	WP_001017129.1	sensor histidine kinase	Regulator
Q7642_RS09655 (Q7642_09645)	liaF	1989329..1990030 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q7642_RS09660 (Q7642_09650)	-	1990045..1990431 (-)	387	WP_001110183.1	hypothetical protein	-
Q7642_RS09665 (Q7642_09655)	map	1990648..1991406 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
Q7642_RS09670 (Q7642_09660)	-	1992049..1993035 (+)	987	WP_000999711.1	aromatic acid exporter family protein	-
Q7642_RS09675 (Q7642_09665)	-	1993211..1993627 (-)	417	WP_025174454.1	hypothetical protein	-
Q7642_RS09680 (Q7642_09670)	-	1993656..1993765 (-)	110	Protein_1866	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40060.56 Da
• Isoelectric Point: 6.0577

>NTDB_id=863322 Q7642_RS09650 WP_001017129.1 1988289..1989332(-) (vraS) [Staphylococcus aureus strain 2008S01-206]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQILILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=863322 Q7642_RS09650 WP_001017129.1 1988289..1989332(-) (vraS) [Staphylococcus aureus strain 2008S01-206]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCT
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCGAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0U1MRG1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997