Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WFE12_RS03120 Genome accession   NZ_CP147877
Coordinates   590379..591020 (+) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis subsp. subtilis str. 168     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 585379..596020
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WFE12_RS03090 ydfE 586574..587197 (-) 624 WP_003243530.1 flavin reductase family protein -
  WFE12_RS03095 ydfF 587287..587967 (+) 681 WP_003244115.1 winged helix-turn-helix domain-containing protein -
  WFE12_RS03100 ydfG 588047..588490 (-) 444 WP_003242768.1 carboxymuconolactone decarboxylase family protein -
  WFE12_RS03105 - 588576..588755 (-) 180 WP_010886421.1 hypothetical protein -
  WFE12_RS03110 - 588752..588895 (-) 144 WP_003243880.1 hypothetical protein -
  WFE12_RS03115 ydfH 589163..590386 (+) 1224 WP_010886422.1 two-component system sensor histidine kinase YdfH -
  WFE12_RS03120 vraR 590379..591020 (+) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  WFE12_RS03125 ydfJ 591136..593310 (+) 2175 WP_003243548.1 MMPL family transporter -
  WFE12_RS03130 cesA 593722..594624 (-) 903 WP_003242638.1 carboxylesterase -
  WFE12_RS03135 ydfK 594826..595515 (-) 690 WP_003242513.1 DUF554 domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=863237 WFE12_RS03120 WP_003244318.1 590379..591020(+) (vraR) [Bacillus subtilis subsp. subtilis str. 168]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=863237 WFE12_RS03120 WP_003244318.1 590379..591020(+) (vraR) [Bacillus subtilis subsp. subtilis str. 168]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTAGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAAGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCCATCAGAGGAAATGTGCTATTGCAGCCTGATATCCTTAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362