NTDB

Overview

Name	pilD	Type	Machinery gene
Locus tag	Q7648_RS08570	Genome accession	NZ_CP131632
Coordinates	1643648..1644508 (+)	Length	286 a.a.
NCBI ID	WP_003689814.1	Uniprot ID	A0AA44U9R8
Organism	Neisseria gonorrhoeae strain 2018S05-288
Function	assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1638648..1649508

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7648_RS08555 (Q7648_08655)	dapD	1639158..1639979 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
Q7648_RS08560 (Q7648_08660)	pgi	1640189..1641832 (-)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
Q7648_RS08565 (Q7648_08665)	pilG	1642342..1643574 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
Q7648_RS08570 (Q7648_08670)	pilD	1643648..1644508 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
Q7648_RS08575 (Q7648_08675)	coaE	1644505..1645137 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
Q7648_RS08580 (Q7648_08680)	-	1645130..1645339 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
Q7648_RS08585 (Q7648_08685)	pilF	1645425..1647101 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
Q7648_RS08595 (Q7648_08695)	-	1647439..1647885 (-)	447	WP_048339558.1	DUF441 domain-containing protein	-
Q7648_RS08600 (Q7648_08700)	-	1647889..1648863 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
Q7648_RS08605 (Q7648_08705)	rplU	1649087..1649395 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

Download Length: 286 a.a. Molecular weight: 31332.34 Da Isoelectric Point: 8.9561

                                >NTDB_id=863045 Q7648_RS08570 WP_003689814.1 1643648..1644508(+) (pilD) [Neisseria gonorrhoeae strain 2018S05-288]

MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW

QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP

LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV

AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

Download Length: 861 bp

                                >NTDB_id=863045 Q7648_RS08570 WP_003689814.1 1643648..1644508(+) (pilD) [Neisseria gonorrhoeae strain 2018S05-288]

ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA

TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA

CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG

CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC

CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT

TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC

TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG

CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC

TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC

GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT

TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)

Type IV leader peptidase family (Peptidase_A24)

(134-242)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441

Detailed information NTG0863045