Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   WDV79_RS07520 Genome accession   NZ_CP147731
Coordinates   1527718..1529697 (-) Length   659 a.a.
NCBI ID   WP_001054074.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain SagR266     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1522718..1534697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WDV79_RS07495 (WDV79_07495) recA 1522726..1523865 (-) 1140 WP_001085741.1 recombinase RecA Machinery gene
  WDV79_RS07500 (WDV79_07500) - 1523939..1525199 (-) 1261 Protein_1489 competence/damage-inducible protein A -
  WDV79_RS07505 (WDV79_07505) - 1525288..1525839 (-) 552 WP_000817341.1 DNA-3-methyladenine glycosylase I -
  WDV79_RS07510 (WDV79_07510) ruvA 1525862..1526452 (-) 591 WP_000272487.1 Holliday junction branch migration protein RuvA Machinery gene
  WDV79_RS07515 (WDV79_07515) - 1526454..1527686 (-) 1233 WP_000657476.1 MFS transporter -
  WDV79_RS07520 (WDV79_07520) hexB 1527718..1529697 (-) 1980 WP_001054074.1 DNA mismatch repair endonuclease MutL Machinery gene
  WDV79_RS07525 (WDV79_07525) - 1529917..1530120 (+) 204 WP_000191849.1 cold shock domain-containing protein -
  WDV79_RS07530 (WDV79_07530) hexA 1530177..1532753 (-) 2577 WP_001118377.1 DNA mismatch repair protein MutS Machinery gene
  WDV79_RS07535 (WDV79_07535) argR 1532810..1533247 (-) 438 WP_001033152.1 arginine repressor -

Sequence

Protein


Download         Length: 659 a.a.        Molecular weight: 73986.20 Da        Isoelectric Point: 5.4718

>NTDB_id=862889 WDV79_RS07520 WP_001054074.1 1527718..1529697(-) (hexB) [Streptococcus agalactiae strain SagR266]
MNLSKIIELPDILANQIAAGEVVERPSSVVKELVENAIDAGSSQITIEVEESGLKKIQITDNGEGMTSEDAVLSLRRHAT
SKIKSQSDLFRIRTLGFRGEALPSIASISLMTIKTATEQGKQGTLLVAKGGNIEKQEVVSSPRGTKILVENLFFNTPARL
KYMKSLQSELAHIIDIVNRLSLAHPEVAFTLINDGKEMTKTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEISGYVS
LPELTRANRNYITLLINGRYIKNFLLNRSILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKERELMSLI
STAISESLKQYDLIPDALENLAKTSTRSVDKPIQTSFSLKQPGLYYDRAKNDFFIGADTVSEPIANFTNLDKSDGSVDND
VKNSVNQGATQSPNIKYASRDQADSENFIHSQDYLSSKQSLNKLVEKLDSEESSTFPELEFFGQMHGTYLFAQGNGGLYI
IDQHAAQERVKYEYYREKIGEVDNSLQQLLVPFLFEFSSSDFLQLQEKMSLLQDVGIFLEPYGNNTFILREHPIWMKEEE
VESGIYEMCDMLLLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARHLLDQLAQCKNPYNCPHGRPVLVNFTKADME
KMFKRIQENHTSLRDLGKY

Nucleotide


Download         Length: 1980 bp        

>NTDB_id=862889 WDV79_RS07520 WP_001054074.1 1527718..1529697(-) (hexB) [Streptococcus agalactiae strain SagR266]
ATGAACTTGTCTAAAATTATTGAATTACCGGATATATTAGCTAACCAGATTGCTGCTGGTGAGGTTGTTGAAAGGCCTAG
TAGCGTCGTTAAAGAATTAGTTGAAAATGCCATAGATGCAGGAAGTAGCCAAATTACCATAGAGGTTGAAGAATCTGGTC
TTAAAAAGATTCAAATAACGGATAACGGTGAAGGGATGACTAGTGAGGATGCCGTTCTCAGTTTACGACGTCACGCTACA
TCCAAAATCAAAAGCCAGAGTGACCTTTTTCGTATTCGGACCTTAGGTTTTCGTGGTGAAGCTCTACCATCAATCGCTTC
GATTAGTTTAATGACGATAAAAACAGCTACAGAGCAAGGGAAACAAGGGACGTTACTTGTTGCTAAAGGGGGAAACATTG
AAAAACAGGAAGTTGTTTCAAGTCCTCGTGGAACAAAAATTTTAGTTGAAAATTTATTCTTTAACACGCCTGCCAGATTG
AAATACATGAAGAGTTTACAGTCTGAACTAGCTCATATTATTGATATTGTTAATAGACTCAGTCTAGCGCATCCGGAAGT
TGCTTTTACACTGATAAATGATGGTAAAGAAATGACTAAAACTAGTGGGACTGGCGATTTGAGACAGGCGATTGCAGGTA
TTTATGGTTTAAATACTGCAAAAAAAATGATTGAGATTTCAAATGCAGATTTAGATTTTGAAATTTCGGGTTATGTAAGT
TTGCCTGAATTGACACGAGCTAACCGAAACTATATTACCCTATTAATTAACGGTCGTTACATTAAAAATTTTCTTTTGAA
CCGCTCAATTCTAGATGGTTATGGTTCAAAGTTGATGGTTGGAAGATTTCCAATTGCTGTCATTGATATTCAGATAGATC
CTTATCTAGCAGATGTCAACGTTCATCCGACTAAGCAAGAGGTGAGAATTTCTAAGGAACGAGAATTAATGAGTTTAATA
AGCACAGCAATTTCTGAGAGTCTTAAACAATATGACTTGATTCCGGATGCTTTAGAGAATTTAGCTAAAACTAGTACCCG
AAGTGTAGATAAGCCTATACAAACAAGCTTCTCACTAAAACAGCCTGGTTTGTATTACGATAGGGCTAAAAATGACTTTT
TTATAGGTGCAGATACTGTATCTGAACCTATTGCTAACTTTACAAACCTTGACAAAAGTGACGGTTCAGTTGACAATGAT
GTAAAAAACTCTGTTAATCAAGGAGCAACGCAGTCTCCTAATATAAAGTATGCTAGTAGAGATCAAGCTGATAGTGAGAA
CTTCATTCATTCTCAGGATTACCTTAGTAGTAAACAGTCACTTAACAAACTTGTTGAAAAATTAGATTCGGAAGAAAGTT
CGACTTTTCCAGAGCTCGAATTTTTTGGTCAAATGCATGGGACCTACTTATTTGCTCAAGGGAATGGTGGGTTGTATATT
ATTGATCAACATGCAGCTCAAGAGCGTGTAAAATACGAGTATTACCGTGAAAAGATAGGTGAGGTTGATAATAGTCTTCA
ACAATTGTTAGTACCATTTCTATTTGAATTTTCAAGTTCAGATTTTCTTCAATTACAAGAAAAAATGTCATTATTACAAG
ATGTTGGTATTTTCTTGGAACCGTATGGTAATAATACTTTCATTTTAAGGGAACATCCAATTTGGATGAAAGAAGAAGAG
GTAGAGTCTGGCATTTATGAAATGTGTGATATGTTGTTGCTCACTAATGAAGTATCAGTGAAAAAATATCGCGCAGAGTT
GGCTATTATGATGTCTTGCAAGCGATCTATTAAAGCAAACCATACGCTAGACGATTACTCAGCACGTCATTTATTAGATC
AGTTAGCGCAATGTAAAAATCCTTATAATTGCCCTCATGGAAGACCTGTTTTAGTTAATTTTACAAAAGCTGATATGGAG
AAAATGTTTAAACGAATCCAAGAAAATCATACAAGCCTCAGGGATTTAGGAAAATATTGA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(460-603)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(211-328)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(27-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.892

100

0.689