Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QAD56_RS04690 Genome accession   NZ_CP130625
Coordinates   984340..986124 (+) Length   594 a.a.
NCBI ID   WP_373930051.1    Uniprot ID   -
Organism   Helicobacter pylori strain BS08     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 979340..991124
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAD56_RS04660 (QAD56_04650) motB 980002..980769 (+) 768 WP_140608582.1 flagellar motor protein MotB -
  QAD56_RS04665 (QAD56_04655) - 980773..981210 (+) 438 WP_001031792.1 hypothetical protein -
  QAD56_RS04670 (QAD56_04660) - 981391..983052 (+) 1662 WP_373930048.1 ABC transporter permease/substrate-binding protein -
  QAD56_RS04675 (QAD56_04665) - 983054..983695 (+) 642 WP_373930049.1 ATP-binding cassette domain-containing protein -
  QAD56_RS04680 (QAD56_04670) - 983707..983886 (-) 180 WP_000468796.1 hypothetical protein -
  QAD56_RS04685 (QAD56_04675) - 983878..984339 (+) 462 WP_000437191.1 hypothetical protein -
  QAD56_RS04690 (QAD56_04680) uvrC 984340..986124 (+) 1785 WP_373930051.1 excinuclease ABC subunit UvrC Machinery gene
  QAD56_RS04695 (QAD56_04685) - 986135..987400 (+) 1266 WP_373930052.1 homoserine dehydrogenase -
  QAD56_RS04700 (QAD56_04690) - 987401..987745 (+) 345 WP_001211661.1 YraN family protein -
  QAD56_RS04705 (QAD56_04695) trxA 987834..988154 (+) 321 WP_000020200.1 thioredoxin -
  QAD56_RS04710 (QAD56_04700) trxB 988160..989095 (+) 936 WP_024773194.1 thioredoxin-disulfide reductase -
  QAD56_RS04715 (QAD56_04705) - 989261..990082 (+) 822 WP_373930055.1 glycosyltransferase family 25 protein -
  QAD56_RS04720 (QAD56_04710) - 990294..990542 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68731.06 Da        Isoelectric Point: 9.6975

>NTDB_id=860761 QAD56_RS04690 WP_373930051.1 984340..986124(+) (uvrC) [Helicobacter pylori strain BS08]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNYRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELKLKMECLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLIPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDA
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGTKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=860761 QAD56_RS04690 WP_373930051.1 984340..986124(+) (uvrC) [Helicobacter pylori strain BS08]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCGCAATAATGAAATCACGCCCA
ATTATCGTGCAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCATTAGTTCAAAAGAAA
AATTGCATCAAAGACAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTAAATTAA
AAATGGAGTGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGTGCAAGCAATAAGGCGGT
GTTGGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTGATACCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGTCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGTTCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGCA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGAGCTTTAGATTTTAATAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGTAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCACTAAAGACATCAT
CCACACCGCTAGCGATACTTTTAAATTGCTCCCCAGCGACAAGCGCTTGCAGTGGGTTCAAAAATTGCGCGATGAAAGCC
ACCGGTACGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.97

100

0.97