Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   QAP04_RS07050 Genome accession   NZ_CP130623
Coordinates   1478470..1480833 (-) Length   787 a.a.
NCBI ID   WP_373961265.1    Uniprot ID   -
Organism   Helicobacter pylori strain BS04     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1473470..1485833
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAP04_RS07025 (QAP04_06995) lpxE 1473948..1474520 (+) 573 WP_373961262.1 lipid A 1-phosphatase LpxE -
  QAP04_RS07030 (QAP04_07000) nspC 1474530..1475747 (-) 1218 WP_373961263.1 carboxynorspermidine decarboxylase -
  QAP04_RS07035 (QAP04_07005) cheV1 1475744..1476709 (-) 966 WP_000785454.1 chemotaxis protein CheV1 -
  QAP04_RS07040 (QAP04_07010) - 1476809..1478149 (-) 1341 WP_373961264.1 COG3014 family protein -
  QAP04_RS07050 (QAP04_07020) comB4 1478470..1480833 (-) 2364 WP_373961265.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  QAP04_RS07055 (QAP04_07025) comB3 1480835..1481098 (-) 264 WP_120824057.1 competence protein ComB Machinery gene
  QAP04_RS07060 (QAP04_07030) comB2 1481098..1481379 (-) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  QAP04_RS07065 (QAP04_07035) - 1481525..1482352 (-) 828 WP_373961266.1 DUF5718 family protein -
  QAP04_RS07070 (QAP04_07040) - 1482445..1483497 (-) 1053 WP_373961267.1 argininosuccinate synthase domain-containing protein -
  QAP04_RS07075 (QAP04_07045) dnaG 1483494..1485173 (-) 1680 WP_373961268.1 DNA primase -
  QAP04_RS07080 (QAP04_07050) groES 1485458..1485814 (+) 357 WP_000671945.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90281.90 Da        Isoelectric Point: 8.7113

>NTDB_id=860749 QAP04_RS07050 WP_373961265.1 1478470..1480833(-) (comB4) [Helicobacter pylori strain BS04]
MLEKLLSAIKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDYQQKIQSDSQYLQAILNQFENKEVYENQYFLVLESTHSLQGVLEHKKKSLMHANMENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAIGVLLYQETPLDIIFSIEPMSVNKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLENLDAQTSLVLGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVGHNNAKEIARVNGHTLVIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTKFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAIFSAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDTITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLESLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=860749 QAP04_RS07050 WP_373961265.1 1478470..1480833(-) (comB4) [Helicobacter pylori strain BS04]
ATGTTAGAAAAGCTTTTGAGCGCTATCAAACAAAAAGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATCCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTCTTCACCGAGCGCCAGATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCGCGCCTTGTGGTTAAAAGGCGTAAAATTGATTATCAACAAAAAATTCAATCTGATTCTCA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAACAAAGAAGTGTATGAGAATCAGTATTTTTTAGTTTTAGAAAGCACTC
ACTCTTTACAAGGCGTTTTAGAGCATAAGAAAAAATCTCTCATGCATGCCAACATGGAAAATTTTAAGGACATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCTTAGAAATCCAGCTCAAAAACTACGCCCCCAAACTCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCGGAATACATTAACGGGTTTGATCTCCCCTTAAAACCCTTAGTAGGGGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAATCAAAAAACCTACAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAGCGCATCACTTCTATAGCGATCGGAGTGCTTTTATACCAAGAGACGCC
ACTAGATATTATCTTTTCTATAGAGCCTATGAGCGTCAATAAAACGCTGAGTTTTTTAAAAGAACGGGCCAAATTCAGCA
TGTCCAATCTCGTTAAAAACGAGCTGCTAGAATACCAGGAACTGGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
TTAAACATTCTTATCAAAGCCCCTAGTTTAGAAAATTTAGACGCTCAAACAAGCTTAGTTTTAGGGCTTTTATTTAAAGA
AAATTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAGGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCACTTAAACC
ACCGCTTGCGTTTTTTAACTTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GGGCCACAACAACGCTAAAGAAATCGCTAGAGTGAATGGGCATACTTTAGTCATAGGGGCTACCGGGAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCTTTTGACAGGATGCAAGGGCTG
TATTCTTTCACAAAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATTAATCCCTTTTGTTTAGAGCCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTCTTTTTGAGCATGTTTGATCTTGCCCCTTCAAGGGATAAAGAAGCTTTAG
AAGACATGAATGCGATTTTTAGCGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGCTTTTAGTTTGCTAGACTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGTTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAACTCCAACGCTTTTTTAAATGTGATAAACCTAGACACCATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTACTTGTTTTATAAAATCTTAGAAGAATCCAGGAAAAACGACAGCGGCTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTACTGAACACCAAAATCAACGCTTTAATCACGCAAGCACGAAAAGCTAATGG
CGTGGTGGTGTTGGCCTTGCAAGATATTTACCAATTGAGCGGGGTCAAAAACGCTCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTACCCGCAAAAAAACGCTAGGGAGTTGAAACACAATTTTAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGGAGTTCTAACATGATTGATGT
GAGTTTGGAGAGTTTGGGGCGTTATTTGAAAATCTTTAATTCGGATTCTAGCCATGTGAACAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGCTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(422-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

98.475

100

0.985