Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QAP04_RS04610 Genome accession   NZ_CP130623
Coordinates   969728..971512 (+) Length   594 a.a.
NCBI ID   WP_373960946.1    Uniprot ID   -
Organism   Helicobacter pylori strain BS04     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 964728..976512
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAP04_RS04580 (QAP04_04565) motB 965492..966265 (+) 774 WP_373960941.1 flagellar motor protein MotB -
  QAP04_RS04585 (QAP04_04570) - 966271..966708 (+) 438 WP_014536745.1 hypothetical protein -
  QAP04_RS04590 (QAP04_04575) - 966777..968438 (+) 1662 WP_373960942.1 ABC transporter permease/substrate-binding protein -
  QAP04_RS04595 (QAP04_04580) - 968442..969083 (+) 642 WP_373960943.1 ATP-binding cassette domain-containing protein -
  QAP04_RS04600 (QAP04_04585) - 969095..969274 (-) 180 WP_373960944.1 hypothetical protein -
  QAP04_RS04605 (QAP04_04590) - 969266..969727 (+) 462 WP_373960945.1 hypothetical protein -
  QAP04_RS04610 (QAP04_04595) uvrC 969728..971512 (+) 1785 WP_373960946.1 excinuclease ABC subunit UvrC Machinery gene
  QAP04_RS04615 (QAP04_04600) - 971523..972788 (+) 1266 WP_373960947.1 homoserine dehydrogenase -
  QAP04_RS04620 (QAP04_04605) - 972789..973133 (+) 345 WP_373960948.1 YraN family protein -
  QAP04_RS04625 (QAP04_04610) trxA 973222..973542 (+) 321 WP_000020189.1 thioredoxin -
  QAP04_RS04630 (QAP04_04615) trxB 973548..974483 (+) 936 WP_120926753.1 thioredoxin-disulfide reductase -
  QAP04_RS04635 (QAP04_04620) - 974698..975519 (+) 822 WP_373960949.1 glycosyltransferase family 25 protein -
  QAP04_RS04640 (QAP04_04625) - 975740..975988 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68732.09 Da        Isoelectric Point: 9.7067

>NTDB_id=860738 QAP04_RS04610 WP_373960946.1 969728..971512(+) (uvrC) [Helicobacter pylori strain BS04]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRISLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRITKIQKI
APFTCMDLAKLYDLDIFAFYGGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAVINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHKYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHAFQKDAYRRYHLKGSDEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=860738 QAP04_RS04610 WP_373960946.1 969728..971512(+) (uvrC) [Helicobacter pylori strain BS04]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCCAATAGCAGCGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAGATCACGCCCA
ACCATCGCATAAGTTTGCGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCTAAATACAATATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTACAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGGGAGCCATAAGGCGGT
GTTAGTGAAAATGTTCATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCGTTATCAATCATTACCAATCGCATTTGCCTTTGATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCATAAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTCAAATTAGAATGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGCATTCCAAAAAGACGCTTATCGGCG
CTACCATTTAAAAGGCTCTGATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCACAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCCAGTAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATATAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.138

100

0.971