Detailed information NTG0860239

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V70_RS10760
• Genome accession: NZ_CP130549
• Coordinates: 2111072..2112115 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA03-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2106072..2117115

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V70_RS10730	-	2106490..2107746 (-)	1257	WP_001795438.1	aminopeptidase	-
Q3V70_RS10735	-	2107749..2107949 (-)	201	WP_000180461.1	DUF1128 family protein	-
Q3V70_RS10740	-	2108096..2108560 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V70_RS10745	-	2108567..2108842 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V70_RS10750	-	2109120..2110337 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
Q3V70_RS10755	vraR	2110453..2111082 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
Q3V70_RS10760	vraS	2111072..2112115 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V70_RS10765	liaF	2112112..2112813 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V70_RS10770	-	2112828..2113214 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V70_RS10775	map	2113431..2114189 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V70_RS10780	-	2114717..2115703 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
Q3V70_RS10785	-	2116193..2116606 (-)	414	WP_001549145.1	hypothetical protein	-
Q3V70_RS10790	-	2116635..2116745 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=860239 Q3V70_RS10760 WP_001017131.1 2111072..2112115(-) (vraS) [Staphylococcus aureus strain SA03-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=860239 Q3V70_RS10760 WP_001017131.1 2111072..2112115(-) (vraS) [Staphylococcus aureus strain SA03-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1