Detailed information NTG0860065

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V66_RS10275
• Genome accession: NZ_CP130543
• Coordinates: 2045768..2046811 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA07-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2040768..2051811

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V66_RS10245	-	2041189..2042445 (-)	1257	WP_001793428.1	aminopeptidase	-
Q3V66_RS10250	-	2042448..2042648 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V66_RS10255	-	2042795..2043259 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V66_RS10260	-	2043266..2043541 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V66_RS10265	-	2043819..2045036 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
Q3V66_RS10270	vraR	2045149..2045778 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
Q3V66_RS10275	vraS	2045768..2046811 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V66_RS10280	liaF	2046808..2047509 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V66_RS10285	-	2047524..2047910 (-)	387	WP_001110182.1	hypothetical protein	-
Q3V66_RS10290	map	2048127..2048885 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
Q3V66_RS10295	-	2049469..2050455 (+)	987	WP_000999712.1	aromatic acid exporter family protein	-
Q3V66_RS10300	-	2050644..2051057 (-)	414	WP_025174370.1	hypothetical protein	-
Q3V66_RS10305	-	2051086..2051196 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=860065 Q3V66_RS10275 WP_001017131.1 2045768..2046811(-) (vraS) [Staphylococcus aureus strain SA07-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=860065 Q3V66_RS10275 WP_001017131.1 2045768..2046811(-) (vraS) [Staphylococcus aureus strain SA07-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1