Detailed information NTG0860020

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V72_RS09275
• Genome accession: NZ_CP130542
• Coordinates: 1906148..1907191 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA08-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1901148..1912191

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V72_RS09245	-	1901570..1902826 (-)	1257	WP_001789555.1	aminopeptidase	-
Q3V72_RS09250	-	1902829..1903029 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V72_RS09255	-	1903176..1903640 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V72_RS09260	-	1903647..1903922 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V72_RS09265	-	1904200..1905417 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
Q3V72_RS09270	vraR	1905529..1906158 (-)	630	WP_000153531.1	two-component system response regulator VraR	Regulator
Q3V72_RS09275	vraS	1906148..1907191 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V72_RS09280	liaF	1907188..1907889 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V72_RS09285	-	1907904..1908290 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V72_RS09290	map	1908507..1909265 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V72_RS09295	-	1909724..1910710 (+)	987	WP_000999720.1	aromatic acid exporter family protein	-
Q3V72_RS09300	-	1911131..1911544 (-)	414	WP_001566709.1	hypothetical protein	-
Q3V72_RS09305	-	1911573..1911683 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=860020 Q3V72_RS09275 WP_001017131.1 1906148..1907191(-) (vraS) [Staphylococcus aureus strain SA08-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=860020 Q3V72_RS09275 WP_001017131.1 1906148..1907191(-) (vraS) [Staphylococcus aureus strain SA08-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1