Detailed information NTG0859892

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V78_RS10135
• Genome accession: NZ_CP130538
• Coordinates: 2021354..2022397 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA11-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2016354..2027397

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V78_RS10105	-	2016775..2018031 (-)	1257	WP_001793428.1	aminopeptidase	-
Q3V78_RS10110	-	2018034..2018234 (-)	201	WP_000180462.1	DUF1128 family protein	-
Q3V78_RS10115	-	2018381..2018845 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V78_RS10120	-	2018852..2019127 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V78_RS10125	-	2019405..2020622 (+)	1218	WP_000037088.1	YihY/virulence factor BrkB family protein	-
Q3V78_RS10130	vraR	2020735..2021364 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
Q3V78_RS10135	vraS	2021354..2022397 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V78_RS10140	liaF	2022394..2023095 (-)	702	WP_000149068.1	cell wall-active antibiotics response protein LiaF	-
Q3V78_RS10145	-	2023110..2023496 (-)	387	WP_043044166.1	hypothetical protein	-
Q3V78_RS10150	map	2023713..2024471 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V78_RS10155	-	2025168..2026154 (+)	987	WP_072419628.1	aromatic acid exporter family protein	-
Q3V78_RS10160	-	2026343..2026756 (-)	414	WP_025174475.1	hypothetical protein	-
Q3V78_RS10165	-	2026785..2026895 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859892 Q3V78_RS10135 WP_001017131.1 2021354..2022397(-) (vraS) [Staphylococcus aureus strain SA11-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859892 Q3V78_RS10135 WP_001017131.1 2021354..2022397(-) (vraS) [Staphylococcus aureus strain SA11-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATTTTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATT
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCGGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1