Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   Q3V88_RS10465 Genome accession   NZ_CP130537
Coordinates   2081525..2082241 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain SA12-SX     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2076525..2087241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q3V88_RS10435 - 2076748..2077374 (+) 627 WP_000522384.1 nitroreductase family protein -
  Q3V88_RS10440 - 2077728..2078513 (+) 786 WP_303262432.1 carbon-nitrogen family hydrolase -
  Q3V88_RS10445 - 2079113..2079247 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  Q3V88_RS10450 agrB 2079483..2080052 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  Q3V88_RS10455 agrD 2080049..2080189 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  Q3V88_RS10460 agrC 2080214..2081506 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  Q3V88_RS10465 agrA 2081525..2082241 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  Q3V88_RS10470 - 2082313..2082422 (+) 110 Protein_2080 hypothetical protein -
  Q3V88_RS10475 - 2082610..2083569 (-) 960 WP_268557193.1 carbohydrate kinase -
  Q3V88_RS10480 - 2083566..2085050 (-) 1485 WP_303262433.1 sucrose-6-phosphate hydrolase -
  Q3V88_RS10485 - 2085199..2086149 (-) 951 WP_000790323.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=859853 Q3V88_RS10465 WP_000688498.1 2081525..2082241(+) (agrA) [Staphylococcus aureus strain SA12-SX]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=859853 Q3V88_RS10465 WP_000688498.1 2081525..2082241(+) (agrA) [Staphylococcus aureus strain SA12-SX]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996