Detailed information NTG0859852

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V88_RS09360
• Genome accession: NZ_CP130537
• Coordinates: 1919756..1920799 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA12-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1914756..1925799

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V88_RS09330	-	1915178..1916434 (-)	1257	WP_001789555.1	aminopeptidase	-
Q3V88_RS09335	-	1916437..1916637 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V88_RS09340	-	1916784..1917248 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V88_RS09345	-	1917255..1917530 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V88_RS09350	-	1917808..1919025 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
Q3V88_RS09355	vraR	1919137..1919766 (-)	630	WP_000153531.1	two-component system response regulator VraR	Regulator
Q3V88_RS09360	vraS	1919756..1920799 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V88_RS09365	liaF	1920796..1921497 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V88_RS09370	-	1921512..1921898 (-)	387	WP_123073707.1	hypothetical protein	-
Q3V88_RS09375	map	1922115..1922873 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V88_RS09380	-	1923336..1924322 (+)	987	WP_000999720.1	aromatic acid exporter family protein	-
Q3V88_RS09385	-	1924741..1925154 (-)	414	WP_001566709.1	hypothetical protein	-
Q3V88_RS09390	-	1925183..1925293 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859852 Q3V88_RS09360 WP_001017131.1 1919756..1920799(-) (vraS) [Staphylococcus aureus strain SA12-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859852 Q3V88_RS09360 WP_001017131.1 1919756..1920799(-) (vraS) [Staphylococcus aureus strain SA12-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1