Detailed information NTG0859598

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V90_RS09750
• Genome accession: NZ_CP130528
• Coordinates: 1986535..1987578 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA18-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1981535..1992578

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V90_RS09720	-	1981956..1983212 (-)	1257	WP_078065149.1	aminopeptidase	-
Q3V90_RS09725	-	1983215..1983415 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V90_RS09730	-	1983562..1984026 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V90_RS09735	-	1984033..1984308 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V90_RS09740	-	1984586..1985803 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
Q3V90_RS09745	vraR	1985916..1986545 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
Q3V90_RS09750	vraS	1986535..1987578 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V90_RS09755	liaF	1987575..1988276 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V90_RS09760	-	1988291..1988677 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V90_RS09765	map	1988894..1989652 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V90_RS09770	-	1990181..1991167 (+)	987	WP_000999708.1	aromatic acid exporter family protein	-
Q3V90_RS09775	-	1991600..1992013 (-)	414	WP_025174552.1	hypothetical protein	-
Q3V90_RS09780	-	1992042..1992152 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859598 Q3V90_RS09750 WP_001017131.1 1986535..1987578(-) (vraS) [Staphylococcus aureus strain SA18-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859598 Q3V90_RS09750 WP_001017131.1 1986535..1987578(-) (vraS) [Staphylococcus aureus strain SA18-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1