Detailed information NTG0859556

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V89_RS09635
• Genome accession: NZ_CP130526
• Coordinates: 1971474..1972517 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA19-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1966474..1977517

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V89_RS09605	-	1966895..1968151 (-)	1257	WP_078065149.1	aminopeptidase	-
Q3V89_RS09610	-	1968154..1968354 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V89_RS09615	-	1968501..1968965 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V89_RS09620	-	1968972..1969247 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V89_RS09625	-	1969525..1970742 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
Q3V89_RS09630	vraR	1970855..1971484 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
Q3V89_RS09635	vraS	1971474..1972517 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V89_RS09640	liaF	1972514..1973215 (-)	702	WP_000149062.1	cell wall-active antibiotics response protein LiaF	-
Q3V89_RS09645	-	1973230..1973616 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V89_RS09650	map	1973833..1974591 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V89_RS09655	-	1975120..1976106 (+)	987	WP_000999708.1	aromatic acid exporter family protein	-
Q3V89_RS09660	-	1976539..1976952 (-)	414	WP_025174552.1	hypothetical protein	-
Q3V89_RS09665	-	1976981..1977091 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859556 Q3V89_RS09635 WP_001017131.1 1971474..1972517(-) (vraS) [Staphylococcus aureus strain SA19-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859556 Q3V89_RS09635 WP_001017131.1 1971474..1972517(-) (vraS) [Staphylococcus aureus strain SA19-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1