Detailed information NTG0859510

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V57_RS09985
• Genome accession: NZ_CP130525
• Coordinates: 2015146..2016189 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA20-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2010146..2021189

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V57_RS09955	-	2010567..2011823 (-)	1257	WP_075583716.1	aminopeptidase	-
Q3V57_RS09960	-	2011826..2012026 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V57_RS09965	-	2012173..2012637 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V57_RS09970	-	2012644..2012919 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V57_RS09975	-	2013197..2014414 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
Q3V57_RS09980	vraR	2014527..2015156 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
Q3V57_RS09985	vraS	2015146..2016189 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V57_RS09990	liaF	2016186..2016887 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V57_RS09995	-	2016902..2017288 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V57_RS10000	map	2017505..2018263 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V57_RS10005	-	2018792..2019778 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
Q3V57_RS10010	-	2020209..2020622 (-)	414	WP_262629378.1	hypothetical protein	-
Q3V57_RS10015	-	2020651..2020761 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859510 Q3V57_RS09985 WP_001017131.1 2015146..2016189(-) (vraS) [Staphylococcus aureus strain SA20-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859510 Q3V57_RS09985 WP_001017131.1 2015146..2016189(-) (vraS) [Staphylococcus aureus strain SA20-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1