Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   Q3V73_RS10290 Genome accession   NZ_CP130523
Coordinates   2076454..2077170 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain SA22-SX     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2071454..2082170
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q3V73_RS10255 groES 2071932..2072216 (-) 285 WP_000917289.1 co-chaperone GroES -
  Q3V73_RS10260 mroQ 2072391..2073134 (+) 744 WP_000197629.1 CPBP family intramembrane glutamic endopeptidase MroQ -
  Q3V73_RS10265 - 2073159..2074346 (-) 1188 WP_031896427.1 SdrH family protein -
  Q3V73_RS10270 - 2074543..2074623 (+) 81 Protein_1991 nitroreductase family protein -
  Q3V73_RS10275 - 2074610..2074981 (+) 372 Protein_1992 accessory gene regulator B family protein -
  Q3V73_RS10280 agrD 2074978..2075118 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  Q3V73_RS10285 agrC 2075143..2076435 (+) 1293 WP_031844950.1 quorum-sensing sensor histidine kinase AgrC -
  Q3V73_RS10290 agrA 2076454..2077170 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  Q3V73_RS10295 - 2077242..2077349 (+) 108 WP_031844951.1 hypothetical protein -
  Q3V73_RS10300 - 2077537..2078496 (-) 960 WP_001253300.1 carbohydrate kinase -
  Q3V73_RS10305 - 2078493..2079977 (-) 1485 WP_000141422.1 sucrose-6-phosphate hydrolase -
  Q3V73_RS10310 - 2080126..2081076 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=859426 Q3V73_RS10290 WP_000688492.1 2076454..2077170(+) (agrA) [Staphylococcus aureus strain SA22-SX]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=859426 Q3V73_RS10290 WP_000688492.1 2076454..2077170(+) (agrA) [Staphylococcus aureus strain SA22-SX]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1