Detailed information NTG0859336

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V59_RS09605
• Genome accession: NZ_CP130520
• Coordinates: 1962548..1963591 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA24-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1957548..1968591

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V59_RS09575	-	1957970..1959226 (-)	1257	WP_078065149.1	aminopeptidase	-
Q3V59_RS09580	-	1959229..1959429 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V59_RS09585	-	1959576..1960040 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V59_RS09590	-	1960047..1960322 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V59_RS09595	-	1960600..1961844 (+)	1245	WP_064125696.1	YihY/virulence factor BrkB family protein	-
Q3V59_RS09600	vraR	1961929..1962558 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
Q3V59_RS09605	vraS	1962548..1963591 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V59_RS09610	liaF	1963588..1964289 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V59_RS09615	-	1964304..1964690 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V59_RS09620	map	1964907..1965665 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V59_RS09625	-	1966194..1967180 (+)	987	WP_000999708.1	aromatic acid exporter family protein	-
Q3V59_RS09630	-	1967613..1968026 (-)	414	WP_025174552.1	hypothetical protein	-
Q3V59_RS09635	-	1968055..1968165 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859336 Q3V59_RS09605 WP_001017131.1 1962548..1963591(-) (vraS) [Staphylococcus aureus strain SA24-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859336 Q3V59_RS09605 WP_001017131.1 1962548..1963591(-) (vraS) [Staphylococcus aureus strain SA24-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1