Detailed information NTG0859221

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V64_RS04240
• Genome accession: NZ_CP130517
• Coordinates: 853996..855039 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA26-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 848996..860039

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V64_RS04210	-	849541..849651 (+)	111	WP_031775032.1	hypothetical protein	-
Q3V64_RS04215	-	849680..850093 (+)	414	WP_001670387.1	hypothetical protein	-
Q3V64_RS04220	-	850524..851510 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
Q3V64_RS04225	map	851922..852680 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V64_RS04230	-	852897..853283 (+)	387	WP_001110179.1	hypothetical protein	-
Q3V64_RS04235	liaF	853298..853999 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V64_RS04240	vraS	853996..855039 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V64_RS04245	vraR	855029..855658 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
Q3V64_RS04250	-	855770..856987 (-)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
Q3V64_RS04255	-	857265..857540 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V64_RS04260	-	857547..858011 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V64_RS04265	-	858158..858358 (+)	201	WP_000180460.1	DUF1128 family protein	-
Q3V64_RS04270	-	858361..859617 (+)	1257	WP_001789555.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859221 Q3V64_RS04240 WP_001017131.1 853996..855039(+) (vraS) [Staphylococcus aureus strain SA26-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859221 Q3V64_RS04240 WP_001017131.1 853996..855039(+) (vraS) [Staphylococcus aureus strain SA26-SX]
ATGAACCACTATATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1