Detailed information NTG0859204

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V60_RS09485
• Genome accession: NZ_CP130516
• Coordinates: 1929167..1930210 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA27-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1924167..1935210

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V60_RS09455	-	1924589..1925845 (-)	1257	WP_072398252.1	aminopeptidase	-
Q3V60_RS09460	-	1925848..1926048 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V60_RS09465	-	1926195..1926659 (+)	465	WP_000567539.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V60_RS09470	-	1926666..1926941 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V60_RS09475	-	1927219..1928436 (+)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
Q3V60_RS09480	vraR	1928548..1929177 (-)	630	WP_000153532.1	two-component system response regulator VraR	Regulator
Q3V60_RS09485	vraS	1929167..1930210 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V60_RS09490	liaF	1930207..1930908 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V60_RS09495	-	1930923..1931309 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V60_RS09500	map	1931526..1932284 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V60_RS09505	-	1932756..1933742 (+)	987	WP_303062047.1	aromatic acid exporter family protein	-
Q3V60_RS09510	-	1934173..1934586 (-)	414	WP_025175030.1	hypothetical protein	-
Q3V60_RS09515	-	1934615..1934725 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859204 Q3V60_RS09485 WP_001017131.1 1929167..1930210(-) (vraS) [Staphylococcus aureus strain SA27-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859204 Q3V60_RS09485 WP_001017131.1 1929167..1930210(-) (vraS) [Staphylococcus aureus strain SA27-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTGAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1